Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   OTU45_RS06205 Genome accession   NZ_CP113114
Coordinates   1247972..1248781 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain NP1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1242972..1253781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS06185 (OTU45_06185) - 1245318..1246304 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  OTU45_RS06190 (OTU45_06190) - 1246593..1247336 (-) 744 WP_001037000.1 potassium channel family protein -
  OTU45_RS06195 (OTU45_06195) - 1247383..1247637 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  OTU45_RS06200 (OTU45_06200) relB 1247639..1247881 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  OTU45_RS06205 (OTU45_06205) vicX 1247972..1248781 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  OTU45_RS06210 (OTU45_06210) micB 1248783..1250132 (-) 1350 WP_000886213.1 cell wall metabolism sensor histidine kinase VicK Regulator
  OTU45_RS06215 (OTU45_06215) micA 1250125..1250829 (-) 705 WP_000722076.1 response regulator YycF Regulator
  OTU45_RS06220 (OTU45_06220) mutY 1250885..1252060 (-) 1176 WP_000886152.1 A/G-specific adenine glycosylase -
  OTU45_RS06225 (OTU45_06225) - 1252157..1252282 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=760336 OTU45_RS06205 WP_001289493.1 1247972..1248781(-) (vicX) [Streptococcus pneumoniae strain NP1]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=760336 OTU45_RS06205 WP_001289493.1 1247972..1248781(-) (vicX) [Streptococcus pneumoniae strain NP1]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773