Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OS088_RS08040 Genome accession   NZ_CP113051
Coordinates   1580533..1581162 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain Viktor     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1575533..1586162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS088_RS08010 - 1575953..1576483 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  OS088_RS08015 - 1576573..1577829 (-) 1257 WP_001793428.1 aminopeptidase -
  OS088_RS08020 - 1577832..1578032 (-) 201 WP_000180460.1 DUF1128 family protein -
  OS088_RS08025 - 1578179..1578643 (+) 465 WP_154284135.1 low molecular weight protein-tyrosine-phosphatase -
  OS088_RS08030 - 1578650..1578925 (+) 276 WP_154284136.1 YtxH domain-containing protein -
  OS088_RS08035 - 1579203..1580420 (+) 1218 WP_000037079.1 YihY/virulence factor BrkB family protein -
  OS088_RS08040 vraR 1580533..1581162 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  OS088_RS08045 vraS 1581152..1582195 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  OS088_RS08050 liaF 1582192..1582893 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  OS088_RS08055 - 1582908..1583294 (-) 387 WP_001110179.1 hypothetical protein -
  OS088_RS08060 map 1583511..1584269 (-) 759 WP_000636144.1 type I methionyl aminopeptidase -
  OS088_RS08065 - 1584736..1585722 (+) 987 WP_154284137.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=759595 OS088_RS08040 WP_000153535.1 1580533..1581162(-) (vraR) [Staphylococcus aureus strain Viktor]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=759595 OS088_RS08040 WP_000153535.1 1580533..1581162(-) (vraR) [Staphylococcus aureus strain Viktor]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAGGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTTGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373