Detailed information NTG0759596

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OS088_RS08045
• Genome accession: NZ_CP113051
• Coordinates: 1581152..1582195 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Viktor
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1576152..1587195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS088_RS08015	-	1576573..1577829 (-)	1257	WP_001793428.1	aminopeptidase	-
OS088_RS08020	-	1577832..1578032 (-)	201	WP_000180460.1	DUF1128 family protein	-
OS088_RS08025	-	1578179..1578643 (+)	465	WP_154284135.1	low molecular weight protein-tyrosine-phosphatase	-
OS088_RS08030	-	1578650..1578925 (+)	276	WP_154284136.1	YtxH domain-containing protein	-
OS088_RS08035	-	1579203..1580420 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
OS088_RS08040	vraR	1580533..1581162 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OS088_RS08045	vraS	1581152..1582195 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OS088_RS08050	liaF	1582192..1582893 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OS088_RS08055	-	1582908..1583294 (-)	387	WP_001110179.1	hypothetical protein	-
OS088_RS08060	map	1583511..1584269 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
OS088_RS08065	-	1584736..1585722 (+)	987	WP_154284137.1	FUSC family protein	-
OS088_RS08070	-	1586153..1586566 (-)	414	WP_154284138.1	hypothetical protein	-
OS088_RS08075	-	1586595..1586705 (-)	111	WP_154284139.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=759596 OS088_RS08045 WP_001017131.1 1581152..1582195(-) (vraS) [Staphylococcus aureus strain Viktor]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=759596 OS088_RS08045 WP_001017131.1 1581152..1582195(-) (vraS) [Staphylococcus aureus strain Viktor]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTTTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTACGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1