Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OS075_RS07020 Genome accession   NZ_CP113029
Coordinates   1364039..1364668 (+) Length   209 a.a.
NCBI ID   WP_000153530.1    Uniprot ID   D9IFM7
Organism   Staphylococcus aureus strain Zoe     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1359039..1369668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS075_RS06995 - 1359418..1360404 (-) 987 WP_000999713.1 FUSC family protein -
  OS075_RS07000 map 1360932..1361690 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  OS075_RS07005 - 1361907..1362293 (+) 387 WP_001110179.1 hypothetical protein -
  OS075_RS07010 liaF 1362308..1363009 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  OS075_RS07015 vraS 1363006..1364049 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  OS075_RS07020 vraR 1364039..1364668 (+) 630 WP_000153530.1 two-component system response regulator VraR Regulator
  OS075_RS07025 - 1364784..1366001 (-) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  OS075_RS07030 - 1366279..1366554 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  OS075_RS07035 - 1366561..1367025 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  OS075_RS07040 - 1367172..1367372 (+) 201 WP_000180461.1 DUF1128 family protein -
  OS075_RS07045 - 1367375..1368631 (+) 1257 WP_267836439.1 aminopeptidase -
  OS075_RS07050 - 1368721..1369251 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23545.29 Da        Isoelectric Point: 5.3889

>NTDB_id=759234 OS075_RS07020 WP_000153530.1 1364039..1364668(+) (vraR) [Staphylococcus aureus strain Zoe]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=759234 OS075_RS07020 WP_000153530.1 1364039..1364668(+) (vraR) [Staphylococcus aureus strain Zoe]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9IFM7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373