Detailed information NTG0755824

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: OOL18_RS05000
• Genome accession: NZ_CP110664
• Coordinates: 1062855..1064057 (-)
• Length: 400 a.a.
• NCBI ID: WP_012263006.1
• Uniprot ID: B0BPG3
• Organism: Actinobacillus pleuropneumoniae strain AP_123
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1057855..1069057

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OOL18_RS04975	lptE	1059655..1060149 (+)	495	WP_005597385.1	LPS assembly lipoprotein LptE	-
OOL18_RS04980	holA	1060258..1061283 (+)	1026	WP_265411089.1	DNA polymerase III subunit delta	-
OOL18_RS04985	yacG	1061360..1061548 (-)	189	WP_005597388.1	DNA gyrase inhibitor YacG	-
OOL18_RS04990	coaE	1061530..1062168 (-)	639	WP_005612207.1	dephospho-CoA kinase	-
OOL18_RS04995	-	1062190..1062828 (-)	639	WP_005604550.1	prepilin peptidase	-
OOL18_RS05000	pilC	1062855..1064057 (-)	1203	WP_012263006.1	type II secretion system F family protein	Machinery gene
OOL18_RS05005	pilB	1064041..1065435 (-)	1395	WP_005601209.1	GspE/PulE family protein	Machinery gene
OOL18_RS05010	pilA	1065453..1065899 (-)	447	WP_215577633.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
OOL18_RS05015	radA	1066081..1067460 (+)	1380	WP_017357656.1	DNA repair protein RadA	-
OOL18_RS05020	-	1067504..1067737 (-)	234	WP_005597399.1	YgjV family protein	-
OOL18_RS05025	folA	1067864..1068352 (-)	489	WP_005597400.1	type 3 dihydrofolate reductase	-

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 45618.11 Da
• Isoelectric Point: 10.3239

>NTDB_id=755824 OOL18_RS05000 WP_012263006.1 1062855..1064057(-) (pilC) [Actinobacillus pleuropneumoniae strain AP_123]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide

• Length: 1203 bp

>NTDB_id=755824 OOL18_RS05000 WP_012263006.1 1062855..1064057(-) (pilC) [Actinobacillus pleuropneumoniae strain AP_123]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTTCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

3D structure

• AlphaFold DB: B0BPG3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	50.126	99.25	0.498
pilC	Haemophilus influenzae Rd KW20	40	100	0.4
pilC	Haemophilus influenzae 86-028NP	39	100	0.39