Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   UKS_RS08010 Genome accession   NZ_AP021887
Coordinates   1583998..1584687 (-) Length   229 a.a.
NCBI ID   WP_156012595.1    Uniprot ID   A0A6H3S757
Organism   Streptococcus sp. 116-D4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1578998..1589687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS07985 (UKS_15430) fni 1579033..1580043 (-) 1011 WP_156012585.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  UKS_RS07990 (UKS_15440) - 1580027..1581034 (-) 1008 WP_156012587.1 phosphomevalonate kinase -
  UKS_RS07995 (UKS_15450) mvaD 1581021..1581974 (-) 954 WP_156012589.1 diphosphomevalonate decarboxylase -
  UKS_RS08000 (UKS_15460) mvk 1581956..1582834 (-) 879 WP_156012591.1 mevalonate kinase -
  UKS_RS08005 (UKS_15470) cbpJ 1582957..1583898 (-) 942 WP_156012593.1 choline-binding protein CbpJ -
  UKS_RS08010 (UKS_15480) covR 1583998..1584687 (-) 690 WP_156012595.1 response regulator transcription factor Regulator
  UKS_RS08015 (UKS_15490) gndA 1584699..1586123 (-) 1425 WP_156012597.1 NADP-dependent phosphogluconate dehydrogenase -
  UKS_RS08020 (UKS_15500) - 1586199..1587608 (-) 1410 WP_156012598.1 cell division site-positioning protein MapZ family protein -
  UKS_RS08025 (UKS_15510) - 1587621..1588778 (-) 1158 WP_156012600.1 class I SAM-dependent RNA methyltransferase -
  UKS_RS08035 (UKS_15520) gpsB 1589265..1589594 (-) 330 WP_000146534.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26738.76 Da        Isoelectric Point: 6.5026

>NTDB_id=75372 UKS_RS08010 WP_156012595.1 1583998..1584687(-) (covR) [Streptococcus sp. 116-D4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLEDMTAQDFADELSRTKPASVIMVL
DHREDLQDQIETIQRFAVSYIYKPVIIDDLVARIAAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=75372 UKS_RS08010 WP_156012595.1 1583998..1584687(-) (covR) [Streptococcus sp. 116-D4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAACAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGAGGATATGACAGCCCAGGATTTTGCAGACGAGCTAAGTCGGACTAAGCCAGCCTCAGTCATTATGGTCTTG
GACCATCGTGAAGATTTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCATATATCTATAAGCCAGTCATTAT
TGATGATTTGGTGGCTCGTATTGCAGCAATTTTCCGAGGTCGGGATTTTATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAAATGATTGCTCTGACGCGT
CGTGAGTATGACCTCTTGGCTACTCTCATGGGAAGCAAGAAAGTCCTGACTCGTGAGCAGTTGCTGGAAAGTGTATGGAA
GTATGAAAGTGCGACCGAAACGAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTTCGTGGTGTTGGTTACACCATGCAAGGATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6H3S757

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.472

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.256

99.127

0.459

Multiple sequence alignment