Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QEP20_RS16975 Genome accession   NZ_CP123977
Coordinates   3260543..3261178 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis subsp. subtilis strain WH60A     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3255543..3266178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEP20_RS16955 (QEP20_16955) yvzF 3256600..3256785 (-) 186 WP_003244599.1 YvzF family protein -
  QEP20_RS16960 (QEP20_16960) gerAA 3256903..3258351 (+) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  QEP20_RS16965 (QEP20_16965) gerAB 3258320..3259417 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  QEP20_RS16970 (QEP20_16970) gerAC 3259414..3260535 (+) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  QEP20_RS16975 (QEP20_16975) vraR 3260543..3261178 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  QEP20_RS16980 (QEP20_16980) liaS 3261156..3262238 (-) 1083 WP_003228512.1 two-component system sensor histidine kinase LiaS -
  QEP20_RS16985 (QEP20_16985) liaF 3262235..3262960 (-) 726 WP_003228510.1 LiaRS two-component regulatory system accessory protein LiaF -
  QEP20_RS16990 (QEP20_16990) liaG 3262994..3263866 (-) 873 WP_003228508.1 DUF4097 domain-containing protein -
  QEP20_RS16995 (QEP20_16995) liaH 3263967..3264644 (-) 678 WP_003228506.1 stress responsive protein LiaH -
  QEP20_RS17000 (QEP20_17000) liaI 3264671..3265051 (-) 381 WP_003228504.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=753594 QEP20_RS16975 WP_003243201.1 3260543..3261178(-) (vraR) [Bacillus subtilis subsp. subtilis strain WH60A]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=753594 QEP20_RS16975 WP_003243201.1 3260543..3261178(-) (vraR) [Bacillus subtilis subsp. subtilis strain WH60A]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408