Detailed information NTG0075330

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: UKS_RS01355
• Genome accession: NZ_AP021887
• Coordinates: 261152..262162 (+)
• Length: 336 a.a.
• NCBI ID: WP_156011452.1
• Uniprot ID: A0A6H3S2F6
• Organism: Streptococcus sp. 116-D4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 256152..267162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UKS_RS01330 (UKS_02340)	folP	256636..257610 (+)	975	WP_173020430.1	dihydropteroate synthase	-
UKS_RS01335 (UKS_02350)	-	257612..258934 (+)	1323	WP_156011449.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
UKS_RS01340 (UKS_02360)	folE	258915..259469 (+)	555	WP_000380917.1	GTP cyclohydrolase I FolE	-
UKS_RS01345 (UKS_02370)	folK	259627..260439 (+)	813	WP_156011450.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
UKS_RS01350 (UKS_02380)	-	260599..260916 (-)	318	WP_156011451.1	DUF960 domain-containing protein	-
UKS_RS01355 (UKS_02390)	ccpA	261152..262162 (+)	1011	WP_156011452.1	catabolite control protein A	Regulator
UKS_RS01360 (UKS_02400)	-	262216..263178 (-)	963	WP_156011453.1	asparaginase	-
UKS_RS01365 (UKS_02410)	-	263244..264635 (+)	1392	WP_156011454.1	Cof-type HAD-IIB family hydrolase	-
UKS_RS01370 (UKS_02420)	-	264818..265270 (-)	453	WP_156011455.1	universal stress protein	-
UKS_RS01375 (UKS_02430)	-	265432..265734 (+)	303	WP_173020431.1	hypothetical protein	-
UKS_RS01380 (UKS_02440)	-	265891..267105 (+)	1215	WP_064276410.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37224.24 Da
• Isoelectric Point: 5.3237

>NTDB_id=75330 UKS_RS01355 WP_156011452.1 261152..262162(+) (ccpA) [Streptococcus sp. 116-D4]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEISVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAMSYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=75330 UKS_RS01355 WP_156011452.1 261152..262162(+) (ccpA) [Streptococcus sp. 116-D4]
ATGAATACAGACGATACAATAACGATTTATGATGTCGCCCGTGAAGCAGGGGTTTCAATGGCGACGGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACCCGTAAAAAAGTGCTTGAGGTGATTGATCGTTTGGATTACCGTCCAAATG
CCGTAGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGAGTTGTGATTCCAAATATTACCAATGGTTATTTCTCA
ACGCTTGCTAAAGGGATTGATGATATCGCTGAAATGTACAAGTACAATATTGTCCTTGCTAATAGTGATGAAGATGATGA
CAAGGAAATTTCAGTTGTCAATACACTGTTTTCTAAGCAAGTGGATGGGATCATCTTTATGGGGTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCACGGACACCAGTTGTTCTTGCAGGGACAGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCTACGATTGATGCGATGAGCTACCTTGCTAAAGAAAATGAGCGCATCGCTTTCGTAAG
CGGTCCGCTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGCTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCCT
ATAGCGAAGGATTGGTATTTGAATCTAAATACACTTATGAAGATGGTTATGCCTTGGCTGAACGCTTGATTTCATCAAAC
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAATGGTTTGGCTGATCACGGTGTGTCTGTGCC
AGAAGAGTTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACGACTATTGCTCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGCTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGCGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGTTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A6H3S2F6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.643	100	0.946
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568