Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QGM68_RS06310 Genome accession   NZ_CP123951
Coordinates   1312908..1313498 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain TL012     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1307908..1318498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QGM68_RS06275 (QGM68_06275) yidF 1308024..1308521 (+) 498 WP_000148063.1 radical SAM protein -
  QGM68_RS06280 (QGM68_06280) emrD 1308529..1309713 (-) 1185 WP_001306726.1 multidrug efflux MFS transporter EmrD -
  QGM68_RS06285 (QGM68_06285) ysdE 1309795..1309869 (+) 75 WP_211180519.1 protein YsdE -
  QGM68_RS06290 (QGM68_06290) tisB 1309993..1310082 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QGM68_RS06295 (QGM68_06295) ivbL 1310647..1310745 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QGM68_RS06300 (QGM68_06300) ilvB 1310851..1312539 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  QGM68_RS06305 (QGM68_06305) ilvN 1312543..1312833 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QGM68_RS06310 (QGM68_06310) letA 1312908..1313498 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QGM68_RS06315 (QGM68_06315) uhpB 1313498..1315000 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QGM68_RS06320 (QGM68_06320) uhpC 1315010..1316329 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QGM68_RS06325 (QGM68_06325) uhpT 1316467..1317858 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=753129 QGM68_RS06310 WP_000633668.1 1312908..1313498(+) (letA) [Escherichia coli strain TL012]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=753129 QGM68_RS06310 WP_000633668.1 1312908..1313498(+) (letA) [Escherichia coli strain TL012]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378