Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | NOV96_RS00355 | Genome accession | NZ_CP110141 |
| Coordinates | 59467..60384 (+) | Length | 305 a.a. |
| NCBI ID | WP_002935296.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain WUSS030 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13840..58580 | 59467..60384 | flank | 887 |
| IScluster/Tn | 60624..68058 | 59467..60384 | flank | 240 |
Gene organization within MGE regions
Location: 13840..68058
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NOV96_RS00075 (NOV96_00075) | ftsH | 13840..15810 (+) | 1971 | WP_240016614.1 | ATP-dependent zinc metalloprotease FtsH | - |
| NOV96_RS00080 (NOV96_00080) | comX/sigX | 16136..16606 (+) | 471 | WP_002936602.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| NOV96_RS00180 (NOV96_00180) | mreC | 23809..24645 (+) | 837 | WP_009908845.1 | rod shape-determining protein MreC | - |
| NOV96_RS00185 (NOV96_00185) | mreD | 24662..25150 (+) | 489 | WP_009908846.1 | rod shape-determining protein MreD | - |
| NOV96_RS00190 (NOV96_00190) | pcsB | 25235..26491 (+) | 1257 | WP_002935338.1 | peptidoglycan hydrolase PcsB | - |
| NOV96_RS00195 (NOV96_00195) | - | 26594..27562 (+) | 969 | WP_002935337.1 | ribose-phosphate diphosphokinase | - |
| NOV96_RS00200 (NOV96_00200) | - | 27649..28827 (+) | 1179 | WP_002935336.1 | pyridoxal phosphate-dependent aminotransferase | - |
| NOV96_RS00205 (NOV96_00205) | recO | 28814..29596 (+) | 783 | WP_002935335.1 | DNA repair protein RecO | - |
| NOV96_RS00210 (NOV96_00210) | plsX | 29593..30600 (+) | 1008 | WP_002935334.1 | phosphate acyltransferase PlsX | - |
| NOV96_RS00215 (NOV96_00215) | - | 30593..30841 (+) | 249 | WP_002935333.1 | phosphopantetheine-binding protein | - |
| NOV96_RS00220 (NOV96_00220) | purC | 30959..31666 (+) | 708 | WP_002935328.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| NOV96_RS00225 (NOV96_00225) | - | 31679..35398 (+) | 3720 | WP_002935327.1 | phosphoribosylformylglycinamidine synthase | - |
| NOV96_RS00230 (NOV96_00230) | purF | 35401..36855 (+) | 1455 | WP_002935326.1 | amidophosphoribosyltransferase | - |
| NOV96_RS00235 (NOV96_00235) | purM | 36911..37933 (+) | 1023 | WP_009908859.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| NOV96_RS00240 (NOV96_00240) | purN | 37930..38481 (+) | 552 | WP_009908860.1 | phosphoribosylglycinamide formyltransferase | - |
| NOV96_RS00245 (NOV96_00245) | purH | 38491..40038 (+) | 1548 | WP_002935323.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| NOV96_RS00250 (NOV96_00250) | - | 40103..40933 (+) | 831 | WP_002935322.1 | DNA adenine methylase | - |
| NOV96_RS00255 (NOV96_00255) | - | 40923..41738 (+) | 816 | WP_032499218.1 | site-specific DNA-methyltransferase | - |
| NOV96_RS00260 (NOV96_00260) | - | 41716..42642 (+) | 927 | WP_002935320.1 | type II restriction endonuclease | - |
| NOV96_RS00265 (NOV96_00265) | - | 42642..43547 (+) | 906 | WP_002935319.1 | type II restriction endonuclease | - |
| NOV96_RS00270 (NOV96_00270) | purD | 43668..44930 (+) | 1263 | WP_002935318.1 | phosphoribosylamine--glycine ligase | - |
| NOV96_RS00275 (NOV96_00275) | purE | 44956..45444 (+) | 489 | WP_002935317.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| NOV96_RS00280 (NOV96_00280) | purK | 45431..46516 (+) | 1086 | WP_002935314.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| NOV96_RS00285 (NOV96_00285) | - | 46503..47426 (+) | 924 | WP_002935313.1 | DUF4268 domain-containing protein | - |
| NOV96_RS00290 (NOV96_00290) | purB | 47461..48753 (+) | 1293 | WP_013730055.1 | adenylosuccinate lyase | - |
| NOV96_RS00295 (NOV96_00295) | - | 49262..50086 (+) | 825 | WP_002935311.1 | ABC transporter ATP-binding protein | - |
| NOV96_RS00300 (NOV96_00300) | - | 50079..50813 (+) | 735 | WP_002935310.1 | ABC transporter permease | - |
| NOV96_RS00305 (NOV96_00305) | - | 51148..51876 (+) | 729 | WP_002935309.1 | DUF2705 family protein | - |
| NOV96_RS00310 (NOV96_00310) | - | 51886..52464 (+) | 579 | WP_002935308.1 | CPBP family intramembrane glutamic endopeptidase | - |
| NOV96_RS00315 (NOV96_00315) | - | 52479..52907 (+) | 429 | WP_002935307.1 | Msa family membrane protein | - |
| NOV96_RS00320 (NOV96_00320) | - | 52900..53772 (+) | 873 | WP_002935305.1 | ABC transporter ATP-binding protein | - |
| NOV96_RS00325 (NOV96_00325) | - | 53778..54548 (+) | 771 | WP_002935304.1 | membrane protein | - |
| NOV96_RS00330 (NOV96_00330) | - | 54551..56263 (+) | 1713 | WP_002935303.1 | ABC transporter ATP-binding protein | - |
| NOV96_RS00335 (NOV96_00335) | - | 56365..56538 (+) | 174 | WP_002935301.1 | hypothetical protein | - |
| NOV96_RS00340 (NOV96_00340) | ruvB | 56833..57834 (+) | 1002 | WP_002935300.1 | Holliday junction branch migration DNA helicase RuvB | - |
| NOV96_RS00345 (NOV96_00345) | - | 57834..58580 (+) | 747 | WP_002935299.1 | GNAT family N-acetyltransferase | - |
| NOV96_RS00350 (NOV96_00350) | - | 58582..59220 (+) | 639 | WP_002935298.1 | HAD-IA family hydrolase | - |
| NOV96_RS00355 (NOV96_00355) | comR | 59467..60384 (+) | 918 | WP_002935296.1 | helix-turn-helix domain-containing protein | Regulator |
| NOV96_RS00360 (NOV96_00360) | - | 60624..61880 (-) | 1257 | WP_002936184.1 | ISL3-like element ISSsu6 family transposase | - |
| NOV96_RS00365 (NOV96_00365) | - | 62216..63418 (-) | 1203 | WP_319803766.1 | IS110-like element ISSsu7 family transposase | - |
| NOV96_RS00370 (NOV96_00370) | - | 63695..64936 (+) | 1242 | WP_240016664.1 | folylpolyglutamate synthase/dihydrofolate synthase family protein | - |
| NOV96_RS00375 (NOV96_00375) | - | 65105..66628 (+) | 1524 | WP_240016665.1 | quinol oxidase | - |
| NOV96_RS00380 (NOV96_00380) | - | 66769..68058 (-) | 1290 | WP_002935134.1 | IS4-like element ISSsu2 family transposase | - |
Sequence
Protein
Download Length: 305 a.a. Molecular weight: 36252.32 Da Isoelectric Point: 4.6744
>NTDB_id=752638 NOV96_RS00355 WP_002935296.1 59467..60384(+) (comR) [Streptococcus suis strain WUSS030]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
Nucleotide
Download Length: 918 bp
>NTDB_id=752638 NOV96_RS00355 WP_002935296.1 59467..60384(+) (comR) [Streptococcus suis strain WUSS030]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis D9 |
100 |
100 |
1 |
| comR | Streptococcus suis P1/7 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus suis 05ZYH33 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus mutans UA159 |
37 |
98.361 |
0.364 |