Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEO85_RS12910 Genome accession   NZ_CP123332
Coordinates   2642118..2642708 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain AREA_494     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2637118..2647708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEO85_RS12895 (QEO85_12880) uhpT 2637758..2639149 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  QEO85_RS12900 (QEO85_12885) uhpC 2639287..2640606 (-) 1320 WP_001296565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QEO85_RS12905 (QEO85_12890) uhpB 2640616..2642118 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QEO85_RS12910 (QEO85_12895) letA 2642118..2642708 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QEO85_RS12915 - 2643192..2644052 (+) 861 Protein_2533 DUF6708 domain-containing protein -
  QEO85_RS12920 (QEO85_12905) ilvN 2644118..2644408 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  QEO85_RS12925 (QEO85_12910) ilvB 2644412..2646100 (-) 1689 WP_000168502.1 acetolactate synthase large subunit -
  QEO85_RS12930 (QEO85_12915) ivbL 2646206..2646304 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  QEO85_RS12935 (QEO85_12920) ysdE 2646549..2646623 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=750802 QEO85_RS12910 WP_000633668.1 2642118..2642708(-) (letA) [Escherichia coli strain AREA_494]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=750802 QEO85_RS12910 WP_000633668.1 2642118..2642708(-) (letA) [Escherichia coli strain AREA_494]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCTGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACAGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378