Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEO87_RS00175 Genome accession   NZ_CP123310
Coordinates   33433..34023 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain AREA_C483     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28433..39023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEO87_RS00140 (QEO87_00140) yidF 28549..29046 (+) 498 WP_000148063.1 radical SAM protein -
  QEO87_RS00145 (QEO87_00145) emrD 29054..30238 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  QEO87_RS00150 (QEO87_00150) ysdE 30320..30394 (+) 75 WP_211180519.1 protein YsdE -
  QEO87_RS00155 (QEO87_00155) tisB 30518..30607 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QEO87_RS00160 (QEO87_00160) ivbL 31172..31270 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  QEO87_RS00165 (QEO87_00165) ilvB 31376..33064 (+) 1689 WP_000168461.1 acetolactate synthase large subunit -
  QEO87_RS00170 (QEO87_00170) ilvN 33068..33358 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QEO87_RS00175 (QEO87_00175) letA 33433..34023 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QEO87_RS00180 (QEO87_00180) uhpB 34023..35525 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QEO87_RS00185 (QEO87_00185) uhpC 35535..36854 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QEO87_RS00190 (QEO87_00190) uhpT 36992..38383 (+) 1392 WP_000879197.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=750078 QEO87_RS00175 WP_000633668.1 33433..34023(+) (letA) [Escherichia coli strain AREA_C483]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=750078 QEO87_RS00175 WP_000633668.1 33433..34023(+) (letA) [Escherichia coli strain AREA_C483]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378