Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4683_RS00250 Genome accession   NZ_CP123247
Coordinates   43748..44338 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain YZMc10-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 38748..49338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4683_RS00235 (N4683_000235) uhpT 39388..40779 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N4683_RS00240 (N4683_000240) uhpC 40917..42236 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N4683_RS00245 (N4683_000245) uhpB 42246..43748 (-) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N4683_RS00250 (N4683_000250) letA 43748..44338 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N4683_RS00255 (N4683_000255) ilvN 44413..44703 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  N4683_RS00260 (N4683_000260) ilvB 44707..46395 (-) 1689 WP_000168432.1 acetolactate synthase large subunit -
  N4683_RS00265 (N4683_000265) ivbL 46501..46599 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  N4683_RS00270 (N4683_000270) tisB 47163..47252 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  N4683_RS00275 (N4683_000275) ysdE 47515..47589 (-) 75 WP_211180519.1 protein YsdE -
  N4683_RS00280 (N4683_000280) emrD 47671..48855 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=749753 N4683_RS00250 WP_000633668.1 43748..44338(-) (letA) [Escherichia coli strain YZMc10-2]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=749753 N4683_RS00250 WP_000633668.1 43748..44338(-) (letA) [Escherichia coli strain YZMc10-2]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378