Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4691_RS00170 Genome accession   NZ_CP123244
Coordinates   32123..32713 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain YZMc3-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 27123..37713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4691_RS00155 (N4691_00155) ilvN 28396..28686 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  N4691_RS00160 (N4691_00160) - 28949..30250 (+) 1302 WP_262940683.1 hypothetical protein -
  N4691_RS00165 (N4691_00165) - 30858..31961 (+) 1104 WP_001308148.1 hypothetical protein -
  N4691_RS00170 (N4691_00170) letA 32123..32713 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N4691_RS00175 (N4691_00175) uhpB 32713..34215 (+) 1503 WP_001308147.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N4691_RS00180 (N4691_00180) uhpC 34225..35544 (+) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N4691_RS00185 (N4691_00185) uhpT 35682..37073 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=749671 N4691_RS00170 WP_000633668.1 32123..32713(+) (letA) [Escherichia coli strain YZMc3-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=749671 N4691_RS00170 WP_000633668.1 32123..32713(+) (letA) [Escherichia coli strain YZMc3-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAGCCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGGGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTGACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378