Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4725_RS00190 Genome accession   NZ_CP123240
Coordinates   37665..38255 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain YZLc1-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 32665..43255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4725_RS00170 (N4725_00170) ilvN 33143..33433 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  N4725_RS00175 (N4725_00175) - 34499..34981 (+) 483 WP_073462037.1 hypothetical protein -
  N4725_RS00180 (N4725_00180) - 35257..36726 (+) 1470 WP_001551899.1 hypothetical protein -
  N4725_RS00190 (N4725_00190) letA 37665..38255 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N4725_RS00195 (N4725_00195) uhpB 38255..39757 (+) 1503 WP_001551898.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N4725_RS00200 (N4725_00200) uhpC 39767..41086 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N4725_RS00205 (N4725_00205) uhpT 41342..42733 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=749587 N4725_RS00190 WP_000633668.1 37665..38255(+) (letA) [Escherichia coli strain YZLc1-3]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=749587 N4725_RS00190 WP_000633668.1 37665..38255(+) (letA) [Escherichia coli strain YZLc1-3]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGTTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTGATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378