Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QET42_RS09630 Genome accession   NZ_CP123237
Coordinates   1958989..1959645 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 4588     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1953989..1964645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QET42_RS09600 (QET42_09600) dcyD 1954869..1955855 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QET42_RS09605 (QET42_09605) tcyL 1955870..1956538 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  QET42_RS09610 (QET42_09610) tcyN 1956535..1957287 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QET42_RS09615 (QET42_09615) sdiA 1957517..1958239 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QET42_RS09620 (QET42_09620) yecF 1958306..1958530 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QET42_RS09625 (QET42_09625) yecU 1958517..1958693 (-) 177 WP_001326718.1 protein YecU -
  QET42_RS24580 - 1958776..1958847 (-) 72 Protein_1884 transcriptional regulator -
  QET42_RS09630 (QET42_09630) letA 1958989..1959645 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QET42_RS09635 (QET42_09635) uvrC 1959642..1961474 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QET42_RS09640 (QET42_09640) pgsA 1961531..1962079 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QET42_RS09660 (QET42_09660) - 1963073..1963354 (+) 282 WP_071527557.1 hypothetical protein -
  QET42_RS09665 (QET42_09665) - 1963544..1963684 (-) 141 WP_000078916.1 Hok/Gef family protein -
  QET42_RS09670 (QET42_09670) - 1963876..1964136 (-) 261 WP_000488111.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=749544 QET42_RS09630 WP_000611335.1 1958989..1959645(+) (letA) [Escherichia coli strain 4588]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=749544 QET42_RS09630 WP_000611335.1 1958989..1959645(+) (letA) [Escherichia coli strain 4588]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486