Detailed information NTG0749272

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: L0P93_RS19500
• Genome accession: NZ_CP109795
• Coordinates: 3824258..3825421 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain B19
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3819258..3830421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L0P93_RS19470 (L0P93_19475)	-	3819523..3819942 (-)	420	WP_277161029.1	TIGR03826 family flagellar region protein	-
L0P93_RS19475 (L0P93_19480)	comFC	3820016..3820705 (-)	690	WP_202627211.1	ComF family protein	Machinery gene
L0P93_RS19480 (L0P93_19485)	-	3820711..3820995 (-)	285	WP_003151389.1	competence protein ComFB	-
L0P93_RS19485 (L0P93_19490)	comFA	3821053..3822438 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
L0P93_RS19490 (L0P93_19495)	-	3822546..3823394 (-)	849	WP_003151387.1	DegV family protein	-
L0P93_RS19495 (L0P93_19500)	degU	3823492..3824181 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
L0P93_RS19500 (L0P93_19505)	degS	3824258..3825421 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
L0P93_RS19505 (L0P93_19510)	-	3825644..3826291 (+)	648	WP_007614107.1	YigZ family protein	-
L0P93_RS19510 (L0P93_19515)	-	3826296..3827510 (+)	1215	WP_277161030.1	LCP family protein	-
L0P93_RS19515 (L0P93_19520)	-	3827609..3828685 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
L0P93_RS19520 (L0P93_19525)	-	3828818..3830014 (-)	1197	WP_029972825.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=749272 L0P93_RS19500 WP_007407484.1 3824258..3825421(-) (degS) [Bacillus velezensis strain B19]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=749272 L0P93_RS19500 WP_007407484.1 3824258..3825421(-) (degS) [Bacillus velezensis strain B19]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951