Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEN55_RS00175 Genome accession   NZ_CP123017
Coordinates   33145..33735 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 19-7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28145..38735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEN55_RS00145 emrD 28627..29811 (-) 1185 WP_060621156.1 multidrug efflux MFS transporter EmrD -
  QEN55_RS00150 ysdE 29893..29967 (+) 75 WP_211180519.1 protein YsdE -
  QEN55_RS00155 tisB 30230..30319 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QEN55_RS00160 ivbL 30884..30982 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QEN55_RS00165 ilvB 31088..32776 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  QEN55_RS00170 ilvN 32780..33070 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QEN55_RS00175 letA 33145..33735 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QEN55_RS00180 uhpB 33735..35237 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QEN55_RS00185 uhpC 35247..36566 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QEN55_RS00190 uhpT 36704..38095 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=744946 QEN55_RS00175 WP_000633668.1 33145..33735(+) (letA) [Escherichia coli strain 19-7]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=744946 QEN55_RS00175 WP_000633668.1 33145..33735(+) (letA) [Escherichia coli strain 19-7]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378