Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   K5706_RS04840 Genome accession   NZ_AP019849
Coordinates   1044181..1046457 (+) Length   758 a.a.
NCBI ID   WP_221071264.1    Uniprot ID   -
Organism   Vibrio alfacsensis strain 04Ya249     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1044181..1052853 1044181..1046457 within 0


Gene organization within MGE regions


Location: 1044181..1052853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K5706_RS04840 comEC 1044181..1046457 (+) 2277 WP_221071264.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  K5706_RS04845 (VA249_08770) msbA 1046489..1048237 (+) 1749 WP_128810527.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  K5706_RS04850 (VA249_08780) lpxK 1048243..1049250 (+) 1008 WP_221071266.1 tetraacyldisaccharide 4'-kinase -
  K5706_RS04855 (VA249_08790) - 1049231..1049410 (+) 180 WP_128810529.1 Trm112 family protein -
  K5706_RS04860 (VA249_08800) kdsB 1049410..1050168 (+) 759 WP_221071269.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  K5706_RS04865 (VA249_08820) - 1050430..1051190 (+) 761 WP_221069472.1 IS5 family transposase -
  K5706_RS04870 (VA249_08830) - 1051297..1052853 (-) 1557 WP_221067840.1 SpoVR family protein -

Sequence

Protein


Download         Length: 758 a.a.        Molecular weight: 85345.48 Da        Isoelectric Point: 9.4609

>NTDB_id=74397 K5706_RS04840 WP_221071264.1 1044181..1046457(+) (comEC) [Vibrio alfacsensis strain 04Ya249]
MTLSDKSWTLVLFVVTVISSAWWPTMPDWRWTLLGMITIGSIIKWRQGVICIGAILGAMVVVVHGNIMEHHKQALFQAGE
DLTIIGTVDSPFTQISHGYEGIVSVSHADSKSLLPFAKPKIRLITPFPLSVNSHFTTQVSMKAITGLRNEAGFDIEQQSL
GNAVLARAVVSSQARWIIRTHTSVRQSIIQSVNREIRHLHHFPLISALAFSDRTRLTHQHWQQLRDSGLLHLISISGLHI
GMAYAFGASIGVCARYMASNLLYLPAVIGLIAAFSYAWLADFSLPTTRAFSVCAIYVMLKYFLVHWSAWRVLLLAVAIQL
SMSPFAFFSMSFWLSYLSVAAVLLAVNEMQQGSKGRKQPLLALLKVQFLLTLLIMPISGYFFVGTSLASIFYNLVFIPWF
GFVVVPVIFLALAVSSSLMTSSITYWFPGVLWQLLDWLLWPMTWALEFAQGSWQPLSVEQSSLVLLVCVLFILRRFFDRS
AWMLLSGVVVMLTLPFSKERQGWRLDVLDVGHGLAVLIEKDSHIMLYDTGKAWAGGSIAEQVIRPVLHRRGYNSIDTLVL
SHTDADHAGGRLYLESQFEPSRKLSSQKLLNYQPCVANNNWTWQGLMVEVVWPPKLVNRAYNPHSCVLRITDPQTHFRVL
LTGDIEAISEWLLTRQAEKINSDVMLVPHHGSKSSSNPKFIHAVNPTLAIASLAKNNQWGMPAESVKAAYQSASVEWLDT
GHDGQISVFINQDNWYFDTKRRESFEPWYRQMLRKGVE

Nucleotide


Download         Length: 2277 bp        

>NTDB_id=74397 K5706_RS04840 WP_221071264.1 1044181..1046457(+) (comEC) [Vibrio alfacsensis strain 04Ya249]
ATGACTCTCTCAGATAAAAGTTGGACCTTGGTGTTATTTGTAGTAACCGTTATATCGTCAGCATGGTGGCCGACAATGCC
AGATTGGCGATGGACGCTATTGGGAATGATTACTATCGGTTCAATCATAAAATGGCGTCAGGGCGTAATCTGCATAGGAG
CAATTTTGGGCGCTATGGTTGTCGTCGTCCATGGCAATATCATGGAGCATCATAAACAAGCCCTTTTTCAAGCAGGTGAG
GATCTTACCATAATTGGCACAGTTGACAGCCCTTTTACGCAAATAAGTCACGGATATGAAGGAATTGTCTCTGTTAGTCA
TGCTGATTCAAAGAGTTTATTACCTTTTGCTAAACCTAAGATCAGGTTGATAACGCCATTTCCGTTATCTGTTAACAGTC
ACTTTACGACACAAGTGTCGATGAAGGCCATTACGGGGTTAAGGAATGAAGCTGGATTCGATATAGAACAACAATCGTTG
GGAAATGCTGTTCTTGCTCGAGCGGTGGTTTCTTCACAAGCGCGATGGATTATTCGGACTCATACTTCTGTTCGGCAAAG
TATTATTCAATCAGTTAATCGCGAGATTAGGCATCTGCATCATTTTCCGCTGATAAGTGCCTTGGCATTCAGTGATCGTA
CTAGGTTGACTCACCAGCATTGGCAGCAGTTACGTGACAGTGGTTTGCTCCATTTGATCTCTATATCCGGTTTGCATATT
GGGATGGCGTACGCTTTTGGCGCATCCATCGGTGTATGTGCTCGTTATATGGCATCAAATTTGTTGTATTTACCTGCGGT
TATAGGTTTGATAGCGGCTTTCTCTTATGCATGGCTAGCTGATTTCTCGTTACCAACAACGCGTGCTTTTTCTGTGTGTG
CGATATACGTGATGCTCAAGTATTTCCTTGTTCATTGGAGTGCTTGGCGTGTTTTATTGCTCGCTGTCGCTATTCAATTG
AGTATGAGTCCATTTGCTTTTTTTAGTATGAGCTTTTGGCTTTCATACCTTTCTGTTGCCGCTGTTTTGCTCGCGGTGAA
TGAGATGCAGCAGGGCAGCAAGGGTAGAAAACAACCGCTTCTAGCGTTACTTAAAGTTCAGTTTTTGCTGACACTTTTGA
TCATGCCTATTAGCGGCTACTTTTTTGTAGGAACAAGTCTAGCCTCTATTTTCTACAATCTTGTTTTTATCCCTTGGTTT
GGTTTTGTGGTTGTTCCAGTGATATTCCTCGCTCTTGCTGTGTCATCATCACTTATGACCTCATCAATCACATATTGGTT
TCCCGGGGTGCTATGGCAATTATTGGATTGGCTGCTTTGGCCTATGACGTGGGCGTTGGAGTTTGCACAAGGCAGTTGGC
AACCGCTTAGCGTTGAGCAATCATCGTTAGTGTTACTTGTTTGTGTACTTTTTATATTGAGGCGCTTTTTTGACCGGTCT
GCGTGGATGCTATTAAGTGGTGTAGTGGTCATGCTTACGTTGCCATTTTCAAAAGAGAGGCAAGGGTGGCGATTAGACGT
ACTCGATGTTGGGCATGGGTTAGCAGTACTCATAGAAAAAGACAGCCACATTATGTTGTATGACACAGGTAAAGCGTGGG
CAGGTGGCAGTATTGCTGAACAGGTGATTCGGCCTGTATTGCATCGCCGAGGCTATAACTCAATCGACACTTTAGTTTTA
AGCCACACTGATGCCGACCATGCTGGTGGCCGGCTTTATCTTGAGTCCCAGTTTGAACCGAGCAGGAAATTGAGTAGCCA
AAAATTGCTAAATTATCAGCCTTGTGTAGCGAATAATAATTGGACTTGGCAGGGCTTAATGGTAGAAGTGGTGTGGCCAC
CTAAGCTTGTCAATCGCGCATACAACCCTCATTCGTGCGTTCTGCGTATCACGGATCCTCAAACCCATTTTCGAGTCCTA
CTCACTGGAGATATTGAAGCGATAAGTGAGTGGTTGTTAACTCGGCAGGCTGAGAAGATAAACAGTGATGTGATGCTCGT
CCCTCATCATGGCAGTAAAAGCTCATCTAATCCCAAATTTATCCATGCTGTGAATCCGACATTGGCGATTGCGTCACTAG
CAAAAAACAATCAGTGGGGTATGCCAGCAGAAAGCGTAAAAGCGGCATATCAGTCCGCAAGCGTTGAATGGCTGGATACA
GGACATGATGGACAAATCAGCGTGTTTATTAATCAAGATAATTGGTATTTTGATACTAAACGTCGAGAGTCATTTGAGCC
CTGGTATAGGCAGATGCTGCGTAAGGGAGTAGAATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-473)

Metallo-beta-lactamase superfamily (Lactamase_B)

(510-688)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio campbellii strain DS40M4

63.456

100

0.635
  comEC Vibrio parahaemolyticus RIMD 2210633

63.325

100

0.633
  comEC Vibrio cholerae strain A1552

41.953

100

0.42

Multiple sequence alignment