Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDY27_RS00180 Genome accession   NZ_CP122832
Coordinates   34147..34737 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ETEC1730     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 29147..39737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDY27_RS00150 (QDY27_00150) ysdE 29711..29785 (+) 75 WP_211180519.1 protein YsdE -
  QDY27_RS00155 (QDY27_00155) tisB 29909..29998 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QDY27_RS00160 (QDY27_00160) - 30314..31534 (+) 1221 WP_032084458.1 ISL3-like element ISKox3 family transposase -
  QDY27_RS00165 (QDY27_00165) ivbL 31886..31984 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  QDY27_RS00170 (QDY27_00170) ilvB 32090..33778 (+) 1689 WP_021570996.1 acetolactate synthase large subunit -
  QDY27_RS00175 (QDY27_00175) ilvN 33782..34072 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QDY27_RS00180 (QDY27_00180) letA 34147..34737 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QDY27_RS00185 (QDY27_00185) uhpB 34737..36239 (+) 1503 WP_094336659.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QDY27_RS00190 (QDY27_00190) uhpC 36249..37568 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QDY27_RS00195 (QDY27_00195) uhpT 37706..39097 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=743224 QDY27_RS00180 WP_000633668.1 34147..34737(+) (letA) [Escherichia coli strain ETEC1730]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=743224 QDY27_RS00180 WP_000633668.1 34147..34737(+) (letA) [Escherichia coli strain ETEC1730]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378