Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDY26_RS00160 Genome accession   NZ_CP122660
Coordinates   28370..28960 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ETEC4073     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23370..33960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDY26_RS00125 (QDY26_00125) yidF 23485..23982 (+) 498 WP_000148061.1 radical SAM protein -
  QDY26_RS00130 (QDY26_00130) emrD 23990..25174 (-) 1185 WP_046788680.1 multidrug efflux MFS transporter EmrD -
  QDY26_RS00135 (QDY26_00135) ysdE 25256..25330 (+) 75 WP_211180519.1 protein YsdE -
  QDY26_RS00140 (QDY26_00140) tisB 25454..25543 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  QDY26_RS00145 (QDY26_00145) ivbL 26108..26206 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  QDY26_RS00150 (QDY26_00150) ilvB 26312..28000 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  QDY26_RS00155 (QDY26_00155) ilvN 28004..28294 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QDY26_RS00160 (QDY26_00160) letA 28370..28960 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QDY26_RS00165 (QDY26_00165) uhpB 28960..30462 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QDY26_RS00170 (QDY26_00170) uhpC 30472..31791 (+) 1320 WP_046788679.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QDY26_RS00175 (QDY26_00175) uhpT 31929..33320 (+) 1392 WP_046788678.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=741983 QDY26_RS00160 WP_000633668.1 28370..28960(+) (letA) [Escherichia coli strain ETEC4073]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=741983 QDY26_RS00160 WP_000633668.1 28370..28960(+) (letA) [Escherichia coli strain ETEC4073]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378