Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   TthHC11_RS10405 Genome accession   NZ_AP019801
Coordinates   1904570..1906603 (+) Length   677 a.a.
NCBI ID   WP_143591819.1    Uniprot ID   -
Organism   Thermus thermophilus strain HC11     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1899570..1911603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TthHC11_RS10370 (TthHC11_20180) - 1900346..1900810 (+) 465 WP_011229049.1 hypothetical protein -
  TthHC11_RS10375 (TthHC11_20190) pfkA 1900787..1901755 (-) 969 WP_011173968.1 6-phosphofructokinase -
  TthHC11_RS10380 (TthHC11_20200) rsmI 1901752..1902546 (-) 795 WP_143591817.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  TthHC11_RS10385 (TthHC11_20210) - 1902548..1903042 (-) 495 WP_011173970.1 hypothetical protein -
  TthHC11_RS10390 (TthHC11_20220) - 1903106..1903633 (-) 528 WP_011173971.1 inorganic diphosphatase -
  TthHC11_RS10395 (TthHC11_20230) - 1903666..1904292 (+) 627 WP_143591818.1 YcxB family protein -
  TthHC11_RS10400 (TthHC11_20240) comEA 1904265..1904573 (+) 309 WP_024119555.1 helix-hairpin-helix domain-containing protein Machinery gene
  TthHC11_RS10405 (TthHC11_20250) comA/comEC 1904570..1906603 (+) 2034 WP_143591819.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  TthHC11_RS10410 (TthHC11_20260) - 1906591..1907400 (-) 810 WP_011229053.1 ParB/RepB/Spo0J family partition protein -
  TthHC11_RS10415 (TthHC11_20270) soj 1907384..1908133 (-) 750 WP_143591820.1 chromosome-partitioning ATPase Soj -
  TthHC11_RS10420 (TthHC11_20280) rsmG 1908127..1908876 (-) 750 WP_143591821.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  TthHC11_RS10425 (TthHC11_20290) mnmG 1908876..1910669 (-) 1794 WP_143591822.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 71930.03 Da        Isoelectric Point: 10.1462

>NTDB_id=74181 TthHC11_RS10405 WP_143591819.1 1904570..1906603(+) (comA/comEC) [Thermus thermophilus strain HC11]
MRPSWTWGVGLGAGALVAAWGLFAPWAFLGLGLLPFLRLPFALGFGLVLARALLFPLPEPPWGAAVEGVFAVRGGFTRAE
GHLLWVSHYPPLPDGRYRLRGRIAPPQGRTNPGGFDQRAWLLSRGAKGVLRAESAEPLGPLPDWREGFRERLGAGLSLEA
REVVEGLVLGDKGGLETAYPLFQRAGLAHLLALSGLHVGVLVGFAVLGLYPLGRWRYLLALALLPFYLLLAGPSPSLVRA
SLMAGLSLLGLFLGLGGAGVVQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALRLPKGPRGYLLGGVAASLA
VQAFLLPLLLHRFGFAPLLAPLANLLALPLVALLVPLGFLKLFLGALPAPLVEPLARGLLLLAGLAAQGPLLRWGEIAPP
GFALYYLGLLPLLFALHRRLPWRRALLLASLPALVGLLAAWPKPLDLWMLDVGQGDALLARMGGGEVLVDGGRAEKGEAV
VRALRALGVEALELLVATHPDADHYGGLFRVIEEVPVGLALLAPGFPEDHPLAQALRARGVPVVRAGAGTRLKVGQGEVR
VLWPEALSGDDNQDGLALLLDFGRGRALLLADLPREVEARLPVGEVEALKVSHHGSQSGTSEVLLERTRPRVALIGVGPN
PFGHPHPEVLERLERHGAEVRRTDQDGAVRVLFGYAW

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=74181 TthHC11_RS10405 WP_143591819.1 1904570..1906603(+) (comA/comEC) [Thermus thermophilus strain HC11]
ATGAGGCCTTCTTGGACCTGGGGAGTGGGGCTTGGGGCGGGGGCTTTGGTGGCCGCCTGGGGGCTTTTCGCGCCTTGGGC
CTTCCTTGGGCTCGGCCTCCTTCCCTTCCTCCGCCTTCCCTTCGCCCTGGGCTTCGGCCTCGTCCTGGCCCGGGCCCTCC
TCTTCCCCTTGCCCGAGCCCCCGTGGGGCGCCGCCGTGGAGGGGGTCTTCGCCGTGAGGGGCGGGTTCACACGGGCGGAG
GGCCACCTCCTCTGGGTGAGCCACTATCCCCCTCTACCGGACGGCCGCTACCGCCTCCGGGGGCGCATCGCCCCGCCCCA
AGGCCGGACCAACCCCGGGGGGTTTGACCAACGGGCCTGGCTCCTGAGCCGGGGGGCCAAGGGGGTGCTCCGGGCCGAAA
GCGCCGAGCCCTTGGGGCCCCTGCCCGACTGGAGGGAGGGGTTCCGGGAACGCCTAGGGGCGGGCCTGAGCCTCGAGGCC
CGGGAGGTGGTGGAGGGCCTGGTCCTCGGGGACAAGGGGGGCTTAGAGACGGCCTACCCCCTCTTCCAGCGGGCGGGCCT
CGCCCACCTCCTGGCGCTCTCTGGCCTTCACGTGGGGGTGCTCGTGGGCTTCGCCGTCCTCGGCCTCTACCCCCTGGGGC
GGTGGCGCTACCTCCTGGCCCTCGCCCTCCTCCCCTTCTACCTCCTCCTCGCCGGGCCGAGCCCCTCCCTGGTGCGGGCG
AGCCTCATGGCGGGCCTGTCCCTCCTCGGCCTCTTCCTGGGCCTTGGGGGGGCCGGGGTGGTCCAGGCCCTGGGGCTCGC
CCTCTTCCTCCAGCTCCTCCTCCGCCCCGAGGCCCTCCTCGGCCTCGGGTTCCAGCTCTCCTACCTCGCGGTGCTGGGCC
TGGCCCTGGTCCTCCCGGCCCTGAGGCTTCCCAAGGGCCCCAGGGGCTATCTCCTCGGGGGCGTGGCCGCAAGCCTGGCC
GTCCAGGCCTTCCTCCTCCCCCTCCTCCTCCACCGCTTCGGCTTCGCCCCCCTCCTCGCCCCCCTCGCCAACCTCCTCGC
CCTCCCCCTGGTGGCCCTCCTCGTGCCCCTCGGCTTCCTCAAGCTCTTCCTCGGCGCCCTCCCCGCCCCCCTGGTGGAGC
CCCTCGCCCGGGGGCTCCTCCTCCTGGCGGGGCTTGCGGCCCAAGGGCCCCTCCTCCGCTGGGGGGAGATCGCCCCCCCA
GGCTTTGCCCTCTACTACCTGGGCCTTCTCCCCCTCCTTTTCGCCCTCCACCGCAGGCTTCCCTGGCGGCGCGCCCTCCT
CCTCGCCTCCCTGCCCGCCCTGGTGGGCCTCCTCGCCGCCTGGCCCAAGCCGCTGGACCTCTGGATGCTGGACGTGGGCC
AGGGGGACGCCCTCCTCGCCCGCATGGGGGGCGGGGAGGTCCTGGTGGACGGGGGACGGGCGGAGAAGGGGGAGGCGGTG
GTCCGGGCCCTCCGCGCCCTCGGGGTGGAGGCCCTGGAGCTTTTGGTGGCCACCCACCCCGACGCGGACCACTACGGGGG
GCTTTTCCGGGTGATAGAGGAGGTTCCCGTGGGCCTTGCCCTCCTCGCCCCCGGCTTCCCCGAGGACCACCCCCTGGCCC
AGGCCCTAAGGGCGCGGGGCGTCCCCGTGGTGCGGGCCGGGGCGGGAACCCGCCTTAAGGTGGGCCAGGGCGAGGTCCGG
GTGCTCTGGCCCGAGGCCCTCTCCGGGGACGACAACCAAGACGGCCTCGCCCTCCTCCTGGACTTCGGCCGGGGACGGGC
CCTCCTCCTCGCCGACCTGCCCCGGGAGGTGGAGGCCAGGCTTCCCGTGGGGGAGGTGGAGGCGCTCAAGGTGAGCCACC
ACGGCTCCCAAAGCGGCACCTCCGAGGTCCTCCTGGAAAGGACGAGGCCACGGGTGGCCCTCATCGGGGTGGGGCCCAAC
CCCTTCGGCCACCCCCACCCCGAGGTCCTGGAGCGCCTTGAGCGCCACGGCGCGGAGGTGCGCCGCACCGACCAGGACGG
GGCGGTGCGCGTCCTCTTCGGCTACGCCTGGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(93-136)

Metallo-beta-lactamase superfamily (Lactamase_B)

(451-635)

Competence protein (Competence)

(167-418)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

99.409

100

0.994
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

41.013

90.399

0.371

Multiple sequence alignment