Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   TthHC11_RS06580 Genome accession   NZ_AP019801
Coordinates   1222202..1223866 (+) Length   554 a.a.
NCBI ID   WP_143591261.1    Uniprot ID   -
Organism   Thermus thermophilus strain HC11     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1217202..1228866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TthHC11_RS06555 (TthHC11_12770) - 1218779..1219759 (-) 981 WP_024119432.1 YpdA family putative bacillithiol disulfide reductase -
  TthHC11_RS06560 (TthHC11_12780) pilA/pilA1 1219917..1220387 (+) 471 WP_011173283.1 GspH/FimT family protein Machinery gene
  TthHC11_RS06565 (TthHC11_12790) - 1220442..1220915 (+) 474 WP_143591260.1 GspH/FimT family protein -
  TthHC11_RS06570 (TthHC11_12800) pilA/pilA2 1220933..1221493 (+) 561 WP_242003979.1 type II secretion system protein Machinery gene
  TthHC11_RS06575 (TthHC11_12810) pilA/pilA3 1221490..1222191 (+) 702 WP_024119434.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  TthHC11_RS06580 (TthHC11_12820) comZ 1222202..1223866 (+) 1665 WP_143591261.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  TthHC11_RS12010 (TthHC11_12830) pilA/pilA4 1224096..1224491 (+) 396 WP_011173287.1 type IV wide pilus major component PilA4 Machinery gene
  TthHC11_RS06590 - 1224548..1225840 (-) 1293 WP_143591263.1 hypothetical protein -
  TthHC11_RS06595 (TthHC11_12850) - 1226097..1226609 (+) 513 WP_011173288.1 hypothetical protein -
  TthHC11_RS06605 (TthHC11_12860) - 1226803..1227903 (+) 1101 WP_143590208.1 transposase -
  TthHC11_RS06610 - 1227882..1228418 (+) 537 Protein_1281 Uma2 family endonuclease -

Sequence

Protein


Download         Length: 554 a.a.        Molecular weight: 59342.08 Da        Isoelectric Point: 8.1219

>NTDB_id=74170 TthHC11_RS06580 WP_143591261.1 1222202..1223866(+) (comZ) [Thermus thermophilus strain HC11]
MNAKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAALFQQYVWREQRGGTGGGGGCF
TSLARGLDLDRDGTITPFVNNRLVLAQNEVVTDANGNPVGRYTVTLYKDAQDGQLFTLVSEGTSGGAKARVQATFRISNT
GYLEQAIFAGTGQANKWLNGGATIRGGVYVVGSPNDPDQYVIEANGNFALYNWYDLTTYSEVANRVEPSYRQVQDLCASL
RVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITGQNVDVCQNNKGVCTEAMGGFDLSDPPPFPILDAKLDSDACSAYP
TWRACLQTKAALRIQRRGNVLSVASPLDVTLPPSCLQAMRSGTLTLDTQNVDCTFTRLDGSRGGFRYTYTGGQGLLEVFG
DVVLEGIDVVLNRPVDYRAQSGSAKSATLAVLKLGGNGGNLDINGNLLPDATFGLFPNHALGLVAEGDAYQRGQYVMAPL
YAGGTFRVVKGNVLFGSVISNQFCTTSAGNQMSCNAGQKAEVVYIRIPKENRPALLPSLRGGKPVFQVLSYERR

Nucleotide


Download         Length: 1665 bp        

>NTDB_id=74170 TthHC11_RS06580 WP_143591261.1 1222202..1223866(+) (comZ) [Thermus thermophilus strain HC11]
GTGAACGCGAAAGGTATCGCCCTCGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTCCAGGCCTTCTACGCCGCCGAGGCGGGGTTGC
AGAAGTACAAGGCCGCCCTCTTCCAGCAGTACGTCTGGCGGGAGCAGCGGGGCGGGACGGGGGGAGGTGGGGGCTGCTTC
ACCTCCCTGGCAAGGGGGCTGGACCTGGACCGGGATGGAACCATCACGCCCTTCGTCAACAACCGGCTGGTCCTGGCGCA
AAACGAGGTGGTTACCGATGCCAACGGCAACCCCGTGGGGCGGTACACGGTAACCCTTTACAAGGACGCCCAAGACGGCC
AGCTCTTCACCCTAGTCTCCGAGGGCACTTCGGGCGGGGCCAAGGCCCGGGTCCAGGCCACCTTCCGCATCAGCAACACG
GGCTACCTGGAGCAGGCCATCTTCGCCGGCACGGGCCAGGCCAACAAGTGGCTGAACGGCGGGGCCACCATCCGGGGCGG
GGTCTACGTAGTGGGAAGCCCTAACGACCCGGACCAATACGTCATAGAGGCCAACGGCAACTTTGCCCTCTACAACTGGT
ACGACCTCACCACCTACTCCGAGGTCGCCAACCGGGTGGAACCCAGCTACCGGCAGGTCCAGGACCTCTGTGCAAGCCTT
AGGGTGCAGTACGGCAAGATTTCCGTGGGAGGAAGCACCCAGATCGGCGAGCCCAACAACAAGGTGAAGGGGGTCTTCGT
GGGCCGGGGTGCCCAGGACATCACCGGGCAGAACGTGGACGTATGCCAGAACAACAAGGGGGTGTGCACCGAGGCCATGG
GGGGATTTGACCTCTCCGACCCGCCCCCCTTCCCCATCCTGGACGCCAAGCTGGACTCCGACGCATGCAGCGCCTACCCT
ACTTGGCGGGCCTGCCTCCAGACCAAGGCCGCTTTAAGGATTCAGCGTCGGGGGAACGTCCTCTCTGTGGCCAGCCCGCT
TGACGTCACCTTGCCCCCTTCCTGCCTCCAAGCCATGCGGTCCGGCACCTTGACTCTGGATACCCAAAACGTAGACTGCA
CCTTCACCCGCCTGGACGGAAGCCGGGGAGGGTTCAGGTACACCTACACGGGCGGGCAGGGGCTTTTGGAGGTCTTCGGC
GACGTGGTACTGGAGGGTATAGACGTGGTGCTCAACCGGCCCGTGGACTATAGGGCCCAGTCGGGGAGCGCCAAGAGCGC
CACCCTTGCGGTGCTGAAGCTTGGCGGCAACGGCGGCAACTTGGACATCAACGGCAACCTCCTCCCCGACGCCACCTTTG
GCCTCTTCCCCAACCACGCCCTGGGCCTCGTGGCCGAAGGGGACGCCTACCAGCGCGGCCAGTACGTGATGGCCCCCCTG
TACGCCGGGGGCACCTTCCGGGTGGTGAAGGGCAACGTCCTCTTCGGCTCCGTCATTAGCAACCAGTTCTGCACCACGAG
CGCCGGGAACCAAATGAGCTGCAACGCCGGCCAGAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGGAGAACCGCCCCG
CGCTCCTGCCGAGCCTCCGCGGGGGAAAGCCCGTCTTCCAGGTGCTCTCCTACGAGCGCCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

94.946

100

0.949

Multiple sequence alignment