Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QC807_RS00175 Genome accession   NZ_CP122492
Coordinates   33145..33735 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain a15     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28145..38735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QC807_RS00145 emrD 28627..29811 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  QC807_RS00150 ysdE 29893..29967 (+) 75 WP_211180519.1 protein YsdE -
  QC807_RS00155 tisB 30230..30319 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QC807_RS00160 ivbL 30884..30982 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QC807_RS00165 ilvB 31088..32776 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  QC807_RS00170 ilvN 32780..33070 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QC807_RS00175 letA 33145..33735 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QC807_RS00180 uhpB 33735..35237 (+) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QC807_RS00185 uhpC 35247..36566 (+) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QC807_RS00190 uhpT 36704..38095 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=740535 QC807_RS00175 WP_000633668.1 33145..33735(+) (letA) [Escherichia coli strain a15]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=740535 QC807_RS00175 WP_000633668.1 33145..33735(+) (letA) [Escherichia coli strain a15]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378