Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QBY78_RS00155 Genome accession   NZ_CP122451
Coordinates   28553..29143 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 82.0312     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23553..34143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBY78_RS00120 (QBY78_00120) yidG 23845..24207 (+) 363 Protein_23 DUF202 domain-containing protein -
  QBY78_RS00125 (QBY78_00125) yidF 24204..24701 (+) 498 WP_021531706.1 radical SAM protein -
  QBY78_RS00130 (QBY78_00130) emrD 24709..25893 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  QBY78_RS00135 (QBY78_00135) ysdE 25975..26049 (+) 75 WP_211180519.1 protein YsdE -
  QBY78_RS00140 (QBY78_00140) ivbL 26294..26392 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  QBY78_RS00145 (QBY78_00145) ilvB 26498..28186 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  QBY78_RS00150 (QBY78_00150) ilvN 28190..28480 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QBY78_RS00155 (QBY78_00155) letA 28553..29143 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  QBY78_RS00160 (QBY78_00160) uhpB 29143..30645 (+) 1503 WP_283154866.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QBY78_RS00165 (QBY78_00165) uhpC 30655..31974 (+) 1320 WP_021522289.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QBY78_RS00170 (QBY78_00170) uhpT 32112..33503 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=739489 QBY78_RS00155 WP_000633668.1 28553..29143(+) (letA) [Escherichia coli strain 82.0312]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=739489 QBY78_RS00155 WP_000633668.1 28553..29143(+) (letA) [Escherichia coli strain 82.0312]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378