Detailed information NTG0073920

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: FOY54_RS01410
• Genome accession: NZ_AP019774
• Coordinates: 269280..271715 (+)
• Length: 811 a.a.
• NCBI ID: WP_064430218.1
• Uniprot ID: A0A6J4CWT3
• Organism: Helicobacter suis strain SNTW101c
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 264280..276715

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOY54_RS01380 (SNTW_02840)	-	265413..266588 (+)	1176	WP_064430215.1	DNA-methyltransferase	-
FOY54_RS01385 (SNTW_02850)	-	266575..267441 (+)	867	WP_064430216.1	CfrBI family restriction endonuclease	-
FOY54_RS01390 (SNTW_02860)	-	267611..268381 (+)	771	WP_064430217.1	hypothetical protein	-
FOY54_RS01395 (SNTW_02870)	comB2	268378..268653 (+)	276	WP_034375713.1	TrbC/VirB2 family protein	Machinery gene
FOY54_RS01400 (SNTW_02880)	comB3	268664..268927 (+)	264	WP_034375715.1	hypothetical protein	Machinery gene
FOY54_RS01405 (SNTW_02890)	-	268947..269267 (+)	321	WP_034375717.1	hypothetical protein	-
FOY54_RS01410 (SNTW_02900)	comB4	269280..271715 (+)	2436	WP_064430218.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
FOY54_RS09500 (SNTW_02910)	-	271720..271929 (+)	210	WP_141556969.1	hypothetical protein	-
FOY54_RS01420 (SNTW_02920)	-	271939..273030 (+)	1092	WP_050780156.1	type IV secretion system protein	-
FOY54_RS01425 (SNTW_02930)	-	273027..274556 (+)	1530	WP_006564108.1	TrbG/VirB9 family P-type conjugative transfer protein	-
FOY54_RS01430 (SNTW_02940)	comB10	274546..275805 (+)	1260	WP_034375723.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 93578.14 Da
• Isoelectric Point: 8.4231

>NTDB_id=73920 FOY54_RS01410 WP_064430218.1 269280..271715(+) (comB4) [Helicobacter suis strain SNTW101c]
MLSDLFTFCKHKSIDYLAGLMPKTYSMVEENNILGIYDSQFLITKQENLVGLLELQGLSYLNLMQQDLEHYFNARKSALD
SIPLGVHLRIVAKRRKEQIKQNTQIDNPYARAIIAGFESKEIYDNRYYLVFESTTGTLKSFFEKKKLEMSTSIAESQDNQ
ERSKQKNITFINKHSMLKAAMQRISHALKDFNPRELSSQEALRFYAEYINGFNIPLKPKMGILSDSYIASDVEFRKDYFL
INFKGKTTYQRFVGVKNYENQTITSVALSCLLHYACELDIIFSIEPLGIFESLHFLKVRKKFSFVNFVKEELDRYIDLVQ
ASRLSMQKIALNVLIRAESKESLDRHTEAVLNLLNNEGLVSKEETIGMIPSYFSFFPGRMDLNYRARYQTSSVMAALILF
EKNNRGFKANSWGDMPLSVFKNLDHSPYLFNFHNQEVQHKGVLAHNIARVNGHTMIIGATGAGKTTLMSYLMMSALKYPN
LDILALDRLNGLYSFTKYFGGVYNNDEEFYINPLTLEDSKENVEFLWSFYTYMLGIESTNKRDKELTEDQNAVRNAIGSM
YADHKKKSKQQEAYEPYTLEEFTNTFIKTQSEQIKGTLEPYLQNPIFNAREDCLEFKSRITTINMDSVINNQKDAGLLAY
YIFYKLIHRALHTNRGFFCFIDEFKSYAQNALMNDKINLIITQARKVNGVVALALQDIHQLDEVKNADSFIKNMGTLIFY
PQKNINTDKLKDQFGIKLSDLERHFLENTNVSSHQILIKNMNDSTSNVVDVSLAALGKYLPIFSSNASTMAHIKHLIKQY
PTSWREVFVHG

Nucleotide

• Length: 2436 bp

>NTDB_id=73920 FOY54_RS01410 WP_064430218.1 269280..271715(+) (comB4) [Helicobacter suis strain SNTW101c]
ATGCTAAGTGATTTGTTTACATTTTGCAAACACAAGAGCATTGACTATCTAGCAGGCTTGATGCCTAAAACCTACTCTAT
GGTTGAGGAAAATAATATTCTAGGCATCTACGATTCCCAATTTTTAATCACCAAACAAGAGAATTTAGTAGGGTTGTTGG
AATTGCAGGGCTTGAGTTACTTGAATTTGATGCAACAGGATTTAGAACATTACTTTAATGCCCGCAAGAGTGCATTAGAT
AGTATCCCTCTAGGTGTGCATCTAAGAATTGTGGCTAAAAGAAGAAAAGAGCAAATCAAGCAGAATACACAGATAGATAA
TCCTTATGCTAGGGCTATCATTGCAGGATTTGAGAGCAAAGAGATTTATGATAACCGCTACTATCTTGTCTTTGAGAGCA
CAACAGGCACGCTTAAGAGCTTTTTTGAAAAGAAAAAGCTAGAGATGAGCACTTCTATAGCAGAGAGCCAAGATAATCAA
GAGCGCTCCAAGCAAAAAAACATCACCTTTATTAACAAGCACTCCATGCTCAAAGCAGCCATGCAGAGAATAAGCCATGC
ACTCAAAGACTTCAACCCTAGAGAGCTTAGCAGCCAAGAAGCCCTTAGATTTTATGCCGAATATATCAATGGCTTTAACA
TTCCTTTAAAACCTAAAATGGGCATTCTCAGCGATAGTTATATTGCTAGTGATGTAGAATTTAGAAAAGATTACTTCCTG
ATCAATTTTAAGGGCAAAACCACCTACCAACGCTTTGTAGGCGTGAAAAACTATGAAAACCAAACCATCACTTCTGTGGC
TCTCTCTTGCTTGTTACACTATGCATGTGAGCTAGACATTATCTTTTCTATAGAGCCTTTGGGCATTTTTGAGAGTTTGC
ATTTCTTAAAAGTACGCAAGAAATTTAGTTTTGTTAATTTTGTCAAAGAGGAGTTAGATAGATACATTGATCTGGTGCAA
GCTTCTAGACTCTCTATGCAAAAAATTGCCTTGAATGTGCTCATCAGAGCAGAAAGCAAAGAGAGTTTAGACAGACACAC
TGAGGCGGTTTTAAACTTGCTTAACAATGAAGGCTTGGTGAGCAAAGAGGAGACTATCGGGATGATACCCTCTTACTTTT
CTTTCTTTCCGGGTCGGATGGACTTAAACTATAGAGCTAGATACCAGACTTCTAGCGTGATGGCGGCCTTGATCTTGTTT
GAAAAGAATAACAGGGGCTTTAAAGCCAACTCTTGGGGGGATATGCCCTTGAGCGTGTTTAAAAACTTAGATCACTCCCC
TTATTTATTCAATTTCCACAACCAAGAAGTGCAACACAAGGGCGTGTTAGCCCACAATATTGCTAGAGTCAATGGACACA
CGATGATTATCGGAGCAACAGGAGCAGGCAAGACCACCTTGATGAGCTATTTGATGATGAGTGCTTTGAAATACCCAAAT
TTAGACATTTTAGCCCTAGATAGACTCAATGGCTTGTATTCCTTCACTAAATACTTTGGAGGGGTGTATAACAATGATGA
GGAGTTTTACATTAACCCTTTGACTTTAGAGGACTCTAAAGAAAATGTAGAGTTTTTGTGGAGCTTTTATACTTACATGC
TAGGCATTGAATCTACCAACAAAAGAGATAAAGAGCTCACAGAAGATCAAAATGCCGTGCGCAATGCTATTGGGAGTATG
TATGCAGACCACAAGAAAAAGAGCAAGCAGCAAGAAGCCTATGAGCCCTATACCTTAGAAGAGTTCACCAACACCTTTAT
TAAGACACAATCTGAACAAATCAAAGGCACTTTAGAGCCTTATTTGCAAAACCCCATTTTCAATGCCAGAGAGGATTGCC
TAGAGTTTAAAAGCCGCATCACCACCATTAATATGGATTCTGTGATCAACAACCAAAAAGACGCAGGGCTACTTGCTTAT
TACATTTTCTATAAGCTCATCCATAGAGCCTTGCACACCAATCGGGGCTTTTTTTGCTTCATTGATGAGTTTAAATCCTA
TGCGCAAAATGCGCTGATGAATGACAAGATTAATCTCATCATCACCCAAGCGCGCAAGGTCAATGGGGTGGTTGCTTTGG
CTTTGCAAGACATCCACCAGTTAGATGAAGTGAAAAATGCCGACAGCTTTATTAAAAATATGGGCACACTGATCTTCTAT
CCCCAAAAGAACATCAATACAGACAAGCTCAAAGACCAGTTTGGCATCAAACTTAGCGATTTAGAACGCCATTTCCTAGA
AAACACCAATGTTTCTAGCCACCAGATTTTAATTAAAAATATGAATGATAGCACTTCTAATGTGGTGGATGTGAGTTTGG
CTGCTCTAGGTAAGTATTTGCCTATCTTTAGTTCTAATGCCAGCACTATGGCACATATCAAGCATTTAATCAAACAATAC
CCAACTAGCTGGAGAGAAGTGTTTGTGCATGGGTAA

Domains

Predicted by InterproScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (187-385)

• Helicase HerA, central domain (DUF87) (450-629)

3D structure

• AlphaFold DB: A0A6J4CWT3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	51.549	99.507	0.513