Detailed information    

insolico Bioinformatically predicted

Overview


Name   comP   Type   Machinery gene
Locus tag   OHM05_RS01085 Genome accession   NZ_CP107272
Coordinates   220934..221383 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain 1130991     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 221632..252673 220934..221383 flank 249


Gene organization within MGE regions


Location: 220934..252673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM05_RS01085 (OHM05_01085) comP 220934..221383 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  OHM05_RS01090 (OHM05_01090) - 221760..221906 (-) 147 WP_003691757.1 hypothetical protein -
  OHM05_RS01095 (OHM05_01095) - 222293..222883 (+) 591 WP_080229150.1 DNA cytosine methyltransferase -
  OHM05_RS01100 (OHM05_01100) - 222880..223251 (+) 372 WP_012503918.1 DNA cytosine methyltransferase -
  OHM05_RS01105 (OHM05_01105) - 223265..224122 (+) 858 WP_012503917.1 ATP-binding protein -
  OHM05_RS01110 (OHM05_01110) - 224312..224908 (+) 597 WP_012503916.1 TIGR02391 family protein -
  OHM05_RS01115 (OHM05_01115) - 224914..225336 (+) 423 WP_003691751.1 very short patch repair endonuclease -
  OHM05_RS01120 (OHM05_01120) - 225475..226805 (+) 1331 Protein_214 replication initiation factor domain-containing protein -
  OHM05_RS01125 (OHM05_01125) - 226850..227140 (+) 291 WP_002216601.1 hypothetical protein -
  OHM05_RS01130 (OHM05_01130) - 227145..227342 (+) 198 WP_003689600.1 hypothetical protein -
  OHM05_RS01135 (OHM05_01135) - 227416..227634 (+) 219 WP_003691584.1 major capsid protein -
  OHM05_RS01140 (OHM05_01140) - 227641..227919 (+) 279 WP_003691583.1 hypothetical protein -
  OHM05_RS01145 (OHM05_01145) - 228047..228364 (+) 318 WP_003689167.1 DUF1132 family protein -
  OHM05_RS01150 (OHM05_01150) - 228306..229874 (+) 1569 WP_162894293.1 IgG-binding virulence factor TspB family protein -
  OHM05_RS01155 (OHM05_01155) - 229875..230165 (+) 291 WP_003689734.1 DUF2523 domain-containing protein -
  OHM05_RS01160 (OHM05_01160) - 230175..231260 (+) 1086 WP_003691565.1 zonular occludens toxin domain-containing protein -
  OHM05_RS01165 (OHM05_01165) - 231381..231740 (+) 360 WP_003689732.1 hypothetical protein -
  OHM05_RS01170 (OHM05_01170) - 232252..233214 (+) 963 WP_048596855.1 IS110 family transposase -
  OHM05_RS01175 (OHM05_01175) - 233543..233923 (-) 381 WP_017147222.1 RusA family crossover junction endodeoxyribonuclease -
  OHM05_RS01180 (OHM05_01180) - 233914..234195 (-) 282 WP_003689109.1 hypothetical protein -
  OHM05_RS01185 (OHM05_01185) - 234224..234373 (-) 150 WP_003689110.1 hypothetical protein -
  OHM05_RS01190 (OHM05_01190) - 234550..235044 (-) 495 WP_041421248.1 DUF3310 domain-containing protein -
  OHM05_RS01195 (OHM05_01195) - 235083..235289 (-) 207 WP_044271496.1 hypothetical protein -
  OHM05_RS01200 (OHM05_01200) - 235359..236141 (-) 783 WP_025456432.1 ATP-binding protein -
  OHM05_RS01205 (OHM05_01205) - 236156..237166 (-) 1011 WP_050153770.1 helix-turn-helix domain-containing protein -
  OHM05_RS01210 (OHM05_01210) - 237163..237390 (-) 228 WP_003691442.1 helix-turn-helix domain-containing protein -
  OHM05_RS01215 (OHM05_01215) - 237771..238487 (+) 717 WP_003695999.1 helix-turn-helix transcriptional regulator -
  OHM05_RS01220 (OHM05_01220) - 238647..239186 (+) 540 WP_003695998.1 Panacea domain-containing protein -
  OHM05_RS01225 (OHM05_01225) - 239187..239546 (+) 360 WP_003691733.1 hypothetical protein -
  OHM05_RS01230 (OHM05_01230) - 239563..239781 (-) 219 WP_003691731.1 hypothetical protein -
  OHM05_RS01235 (OHM05_01235) - 240265..240465 (+) 201 WP_047917349.1 hypothetical protein -
  OHM05_RS01240 (OHM05_01240) - 240498..240974 (+) 477 WP_002255718.1 DUF6948 domain-containing protein -
  OHM05_RS01245 (OHM05_01245) - 240971..241258 (+) 288 WP_047926276.1 hypothetical protein -
  OHM05_RS01250 (OHM05_01250) - 241400..241732 (+) 333 WP_050155386.1 hypothetical protein -
  OHM05_RS01255 (OHM05_01255) - 241885..242160 (+) 276 WP_082295533.1 NGO1622 family putative holin -
  OHM05_RS01260 (OHM05_01260) - 242157..242318 (+) 162 WP_003693867.1 hypothetical protein -
  OHM05_RS01265 (OHM05_01265) - 242387..243073 (+) 687 WP_033910330.1 phage replication initiation protein, NGO0469 family -
  OHM05_RS01270 (OHM05_01270) - 243213..243395 (+) 183 WP_003691535.1 hypothetical protein -
  OHM05_RS01275 (OHM05_01275) - 243392..243883 (+) 492 WP_047916888.1 siphovirus Gp157 family protein -
  OHM05_RS01280 (OHM05_01280) - 243935..244150 (+) 216 WP_003691538.1 hypothetical protein -
  OHM05_RS01285 (OHM05_01285) - 244261..245244 (+) 984 WP_047952517.1 hypothetical protein -
  OHM05_RS01290 (OHM05_01290) - 245241..245471 (+) 231 WP_003695893.1 hypothetical protein -
  OHM05_RS01295 (OHM05_01295) - 245443..246390 (+) 948 WP_012503904.1 hypothetical protein -
  OHM05_RS01300 (OHM05_01300) - 246498..246764 (+) 267 WP_003689557.1 pyocin activator PrtN family protein -
  OHM05_RS01305 (OHM05_01305) - 246814..247968 (-) 1155 WP_003697468.1 tyrosine-type recombinase/integrase -
  OHM05_RS01310 (OHM05_01310) dusA 248088..249104 (+) 1017 WP_003689555.1 tRNA dihydrouridine(20/20a) synthase DusA -
  OHM05_RS01315 (OHM05_01315) gluQRS 249174..250061 (-) 888 WP_003689554.1 tRNA glutamyl-Q(34) synthetase GluQRS -
  OHM05_RS01320 (OHM05_01320) - 250078..250368 (-) 291 WP_003689553.1 hypothetical protein -
  OHM05_RS01325 (OHM05_01325) - 250373..250507 (-) 135 WP_012503902.1 hypothetical protein -
  OHM05_RS01330 (OHM05_01330) tal 250519..251574 (-) 1056 WP_003689551.1 transaldolase -
  OHM05_RS01335 (OHM05_01335) - 251671..252645 (+) 975 WP_003689550.1 SIS domain-containing protein -

Sequence


Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=739061 OHM05_RS01085 WP_002214937.1 220934..221383(+) (comP) [Neisseria gonorrhoeae strain 1130991]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=739061 OHM05_RS01085 WP_002214937.1 220934..221383(+) (comP) [Neisseria gonorrhoeae strain 1130991]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1

  comP Neisseria meningitidis 8013

99.329

100

0.993

  comP Neisseria subflava NJ9703

49.66

98.658

0.49