Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | NDN54_RS08525 | Genome accession | NZ_CP107266 |
| Coordinates | 1619082..1619531 (-) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain 9112 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1586284..1618833 | 1619082..1619531 | flank | 249 |
Gene organization within MGE regions
Location: 1586284..1619531
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDN54_RS08260 (NDN54_08260) | - | 1586312..1587286 (-) | 975 | WP_003689550.1 | SIS domain-containing protein | - |
| NDN54_RS08265 (NDN54_08265) | tal | 1587383..1588438 (+) | 1056 | WP_003695503.1 | transaldolase | - |
| NDN54_RS08270 (NDN54_08270) | - | 1588450..1588584 (+) | 135 | WP_012503902.1 | hypothetical protein | - |
| NDN54_RS08275 (NDN54_08275) | - | 1588589..1588879 (+) | 291 | WP_003689553.1 | hypothetical protein | - |
| NDN54_RS08280 (NDN54_08280) | gluQRS | 1588896..1589783 (+) | 888 | WP_003689554.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| NDN54_RS08285 (NDN54_08285) | dusA | 1589853..1590869 (-) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| NDN54_RS08290 (NDN54_08290) | - | 1590989..1592143 (+) | 1155 | WP_003693486.1 | tyrosine-type recombinase/integrase | - |
| NDN54_RS08295 (NDN54_08295) | - | 1592193..1592459 (-) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| NDN54_RS08300 (NDN54_08300) | - | 1592567..1593715 (-) | 1149 | WP_003705649.1 | hypothetical protein | - |
| NDN54_RS08305 (NDN54_08305) | - | 1593712..1594695 (-) | 984 | WP_041421310.1 | phage associated protein | - |
| NDN54_RS08310 (NDN54_08310) | - | 1594806..1595021 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NDN54_RS08315 (NDN54_08315) | - | 1595073..1595564 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| NDN54_RS08320 (NDN54_08320) | - | 1595561..1595743 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NDN54_RS08325 (NDN54_08325) | - | 1595883..1596569 (-) | 687 | WP_010359969.1 | phage replication initiation protein, NGO0469 family | - |
| NDN54_RS08330 (NDN54_08330) | - | 1596638..1596799 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| NDN54_RS08335 (NDN54_08335) | - | 1596796..1597074 (-) | 279 | WP_041421244.1 | NGO1622 family putative holin | - |
| NDN54_RS08340 (NDN54_08340) | - | 1597227..1597559 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| NDN54_RS08345 (NDN54_08345) | - | 1597700..1597987 (-) | 288 | WP_041421246.1 | hypothetical protein | - |
| NDN54_RS08350 (NDN54_08350) | - | 1597984..1598460 (-) | 477 | WP_012504141.1 | DUF6948 domain-containing protein | - |
| NDN54_RS08355 (NDN54_08355) | - | 1598493..1598693 (-) | 201 | WP_003704298.1 | hypothetical protein | - |
| NDN54_RS08360 (NDN54_08360) | - | 1599178..1599396 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| NDN54_RS08365 (NDN54_08365) | - | 1599413..1599772 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| NDN54_RS08370 (NDN54_08370) | - | 1599773..1600312 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| NDN54_RS08375 (NDN54_08375) | - | 1600472..1601176 (-) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| NDN54_RS08380 (NDN54_08380) | - | 1601304..1601519 (+) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| NDN54_RS08385 (NDN54_08385) | - | 1601599..1601754 (+) | 156 | WP_003703527.1 | hypothetical protein | - |
| NDN54_RS08390 (NDN54_08390) | - | 1601731..1601919 (-) | 189 | WP_003698903.1 | hypothetical protein | - |
| NDN54_RS08395 (NDN54_08395) | - | 1602092..1602319 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDN54_RS08400 (NDN54_08400) | - | 1602316..1602453 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| NDN54_RS08405 (NDN54_08405) | - | 1602437..1603501 (+) | 1065 | WP_003689134.1 | hypothetical protein | - |
| NDN54_RS08410 (NDN54_08410) | - | 1603498..1604859 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDN54_RS08415 (NDN54_08415) | - | 1604876..1605106 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NDN54_RS08420 (NDN54_08420) | - | 1605197..1605691 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NDN54_RS08425 (NDN54_08425) | - | 1606073..1606222 (+) | 150 | WP_041421445.1 | hypothetical protein | - |
| NDN54_RS08430 (NDN54_08430) | - | 1606251..1606532 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDN54_RS08435 (NDN54_08435) | - | 1606523..1606903 (+) | 381 | WP_033910829.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDN54_RS08440 (NDN54_08440) | - | 1607232..1608194 (-) | 963 | WP_048596800.1 | IS110 family transposase | - |
| NDN54_RS08445 (NDN54_08445) | - | 1608720..1609079 (-) | 360 | WP_003689732.1 | hypothetical protein | - |
| NDN54_RS08450 (NDN54_08450) | - | 1609200..1610272 (-) | 1073 | Protein_1635 | zonular occludens toxin domain-containing protein | - |
| NDN54_RS08455 (NDN54_08455) | - | 1610282..1610572 (-) | 291 | WP_012503936.1 | DUF2523 domain-containing protein | - |
| NDN54_RS08460 (NDN54_08460) | - | 1610551..1612140 (-) | 1590 | WP_172761357.1 | IgG-binding virulence factor TspB family protein | - |
| NDN54_RS08465 (NDN54_08465) | - | 1612082..1612399 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| NDN54_RS08470 (NDN54_08470) | - | 1612527..1612805 (-) | 279 | WP_003691583.1 | hypothetical protein | - |
| NDN54_RS08475 (NDN54_08475) | - | 1612812..1613030 (-) | 219 | WP_003691584.1 | major capsid protein | - |
| NDN54_RS08480 (NDN54_08480) | - | 1613104..1613301 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| NDN54_RS08485 (NDN54_08485) | - | 1613306..1613596 (-) | 291 | WP_012503914.1 | hypothetical protein | - |
| NDN54_RS08490 (NDN54_08490) | - | 1613641..1614990 (-) | 1350 | WP_025455830.1 | replication initiation factor domain-containing protein | - |
| NDN54_RS08495 (NDN54_08495) | - | 1615129..1615551 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| NDN54_RS08500 (NDN54_08500) | - | 1615557..1616153 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| NDN54_RS08505 (NDN54_08505) | - | 1616343..1617200 (-) | 858 | WP_012503917.1 | ATP-binding protein | - |
| NDN54_RS08510 (NDN54_08510) | - | 1617214..1617648 (-) | 435 | WP_229684538.1 | DNA cytosine methyltransferase | - |
| NDN54_RS08515 (NDN54_08515) | - | 1617582..1618190 (-) | 609 | WP_080229275.1 | DNA cytosine methyltransferase | - |
| NDN54_RS08520 (NDN54_08520) | - | 1618559..1618705 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| NDN54_RS08525 (NDN54_08525) | comP | 1619082..1619531 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=738931 NDN54_RS08525 WP_002214937.1 1619082..1619531(-) (comP) [Neisseria gonorrhoeae strain 9112]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=738931 NDN54_RS08525 WP_002214937.1 1619082..1619531(-) (comP) [Neisseria gonorrhoeae strain 9112]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |