Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QA712_RS07295 Genome accession   NZ_CP121539
Coordinates   1342959..1344929 (-) Length   656 a.a.
NCBI ID   WP_332529456.1    Uniprot ID   -
Organism   Lactococcus lactis strain MA5     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1337959..1349929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS07265 (QA712_07260) - 1338413..1338613 (+) 201 WP_047207027.1 hypothetical protein -
  QA712_RS07270 (QA712_07265) glnA 1338672..1340012 (-) 1341 WP_003131984.1 type I glutamate--ammonia ligase -
  QA712_RS07275 (QA712_07270) - 1340074..1340439 (-) 366 WP_003131985.1 MerR family transcriptional regulator -
  QA712_RS07280 (QA712_07275) - 1340540..1340977 (-) 438 WP_029344573.1 low molecular weight protein-tyrosine-phosphatase -
  QA712_RS07285 (QA712_07280) ruvB 1341126..1342127 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  QA712_RS07290 (QA712_07285) ruvA 1342254..1342847 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  QA712_RS07295 (QA712_07290) hexB 1342959..1344929 (-) 1971 WP_332529456.1 DNA mismatch repair endonuclease MutL Machinery gene
  QA712_RS07300 (QA712_07295) - 1345060..1345770 (-) 711 WP_372756848.1 hypothetical protein -
  QA712_RS07305 (QA712_07300) hexA 1345884..1348406 (-) 2523 WP_311803301.1 DNA mismatch repair protein MutS Machinery gene
  QA712_RS07310 (QA712_07305) - 1348600..1348947 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -
  QA712_RS07315 (QA712_07310) - 1349289..1349591 (-) 303 WP_230318011.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73693.82 Da        Isoelectric Point: 5.1210

>NTDB_id=737320 QA712_RS07295 WP_332529456.1 1342959..1344929(-) (hexB) [Lactococcus lactis strain MA5]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLVAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSLP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKESLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQASNDSSEQTFDNFTE
NQLNTDAVSEKITDSTVERTTEITDNSLENTVSNFEIDFDNEAKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLQKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=737320 QA712_RS07295 WP_332529456.1 1342959..1344929(-) (hexB) [Lactococcus lactis strain MA5]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGGGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCAGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCGACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGTGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAGTTGCTAAAGGCGGAAATATCGAAACTT
TAGAACCGCTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAACACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGCTCCGACTTAGATTTTGAACTAACAGGTTATGTCAGCTTACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGGTATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GAGCCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAGTGAAAAAATTACTGACAGCACTGTTGAAAGAACAACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGCAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCGCAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTACTTGGTTGACCAACATGCG
GCTCAAGAGCGAATAAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCCAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGACGCCGAGTCAGCTAGAGCTTTACTCGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)

MutL C terminal dimerisation domain (MutL_C)

(455-598)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

57.143

99.238

0.567