Detailed information NTG0073531

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FNL60_RS05945
• Genome accession: NZ_AP019720
• Coordinates: 1154726..1155958 (-)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain NBRC 13955
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1149726..1160958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FNL60_RS05925 (SM3g_10900)	-	1150055..1151317 (+)	1263	WP_002280024.1	PLP-dependent aminotransferase family protein	-
FNL60_RS05930 (SM3g_10910)	mmuM	1151451..1152401 (-)	951	WP_002264316.1	homocysteine S-methyltransferase	-
FNL60_RS05935	-	1152411..1153788 (-)	1378	Protein_1099	amino acid permease	-
FNL60_RS05940 (SM3g_10940)	yihA	1154117..1154710 (-)	594	WP_002262817.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FNL60_RS05945 (SM3g_10950)	clpX	1154726..1155958 (-)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FNL60_RS05950 (SM3g_10960)	-	1155983..1156153 (-)	171	WP_002262815.1	hypothetical protein	-
FNL60_RS05955 (SM3g_10970)	-	1156171..1156683 (-)	513	WP_002262814.1	dihydrofolate reductase	-
FNL60_RS05960 (SM3g_10980)	pnuC	1156768..1157547 (-)	780	WP_002266473.1	nicotinamide riboside transporter PnuC	-
FNL60_RS05965 (SM3g_10990)	-	1157664..1158503 (-)	840	WP_002264319.1	thymidylate synthase	-
FNL60_RS05970 (SM3g_11000)	-	1158711..1159886 (+)	1176	WP_002267988.1	hydroxymethylglutaryl-CoA synthase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=73531 FNL60_RS05945 WP_002262816.1 1154726..1155958(-) (clpX) [Streptococcus mutans strain NBRC 13955]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=73531 FNL60_RS05945 WP_002262816.1 1154726..1155958(-) (clpX) [Streptococcus mutans strain NBRC 13955]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578