Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LLNCDO1820_RS08845 Genome accession   NZ_CP120927
Coordinates   1728884..1730254 (-) Length   456 a.a.
NCBI ID   WP_010906089.1    Uniprot ID   Q9CF07
Organism   Lactococcus lactis subsp. lactis strain NCDO1820     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1723884..1735254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLNCDO1820_RS08830 (LLNCDO1820_08825) - 1725055..1726488 (-) 1434 WP_010906086.1 6-phospho-beta-glucosidase -
  LLNCDO1820_RS08835 (LLNCDO1820_08830) yidD 1726611..1726877 (-) 267 WP_010906087.1 membrane protein insertion efficiency factor YidD -
  LLNCDO1820_RS08840 (LLNCDO1820_08835) - 1726994..1728736 (-) 1743 WP_010906088.1 1-deoxy-D-xylulose-5-phosphate synthase -
  LLNCDO1820_RS08845 (LLNCDO1820_08840) ciaH 1728884..1730254 (-) 1371 WP_010906089.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LLNCDO1820_RS08850 (LLNCDO1820_08845) ciaR 1730347..1731015 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  LLNCDO1820_RS08855 (LLNCDO1820_08850) - 1731193..1732167 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  LLNCDO1820_RS08860 (LLNCDO1820_08855) - 1732320..1734575 (-) 2256 WP_010906090.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51278.80 Da        Isoelectric Point: 9.3135

>NTDB_id=735194 LLNCDO1820_RS08845 WP_010906089.1 1728884..1730254(-) (ciaH) [Lactococcus lactis subsp. lactis strain NCDO1820]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGDLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=735194 LLNCDO1820_RS08845 WP_010906089.1 1728884..1730254(-) (ciaH) [Lactococcus lactis subsp. lactis strain NCDO1820]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAATTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCGATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae D39

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae R6

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae TIGR4

44.321

98.465

0.436