Detailed information    

insolico Bioinformatically predicted

Overview


Name   comP   Type   Machinery gene
Locus tag   LLE33_RS08130 Genome accession   NZ_CP106767
Coordinates   1541751..1542200 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain 10610     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1508217..1541502 1541751..1542200 flank 249


Gene organization within MGE regions


Location: 1508217..1542200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLE33_RS07855 (LLE33_07855) - 1508245..1509219 (-) 975 WP_003689550.1 SIS domain-containing protein -
  LLE33_RS07860 (LLE33_07860) tal 1509316..1510371 (+) 1056 WP_003689551.1 transaldolase -
  LLE33_RS07865 (LLE33_07865) - 1510383..1510517 (+) 135 WP_003703570.1 hypothetical protein -
  LLE33_RS07870 (LLE33_07870) - 1510522..1510812 (+) 291 WP_003689553.1 hypothetical protein -
  LLE33_RS07875 (LLE33_07875) gluQRS 1510829..1511716 (+) 888 WP_003693489.1 tRNA glutamyl-Q(34) synthetase GluQRS -
  LLE33_RS07880 (LLE33_07880) dusA 1511786..1512802 (-) 1017 WP_003693487.1 tRNA dihydrouridine(20/20a) synthase DusA -
  LLE33_RS07885 (LLE33_07885) - 1512922..1514076 (+) 1155 WP_003693486.1 tyrosine-type recombinase/integrase -
  LLE33_RS07890 (LLE33_07890) - 1514126..1514392 (-) 267 WP_003689557.1 pyocin activator PrtN family protein -
  LLE33_RS07895 (LLE33_07895) - 1514500..1515648 (-) 1149 WP_134994054.1 SAM-dependent methyltransferase -
  LLE33_RS07900 (LLE33_07900) - 1515645..1516628 (-) 984 WP_134994057.1 hypothetical protein -
  LLE33_RS07905 (LLE33_07905) - 1516739..1516954 (-) 216 WP_003691538.1 hypothetical protein -
  LLE33_RS07910 (LLE33_07910) - 1517006..1517497 (-) 492 WP_033911206.1 siphovirus Gp157 family protein -
  LLE33_RS07915 (LLE33_07915) - 1517494..1517676 (-) 183 WP_003691535.1 hypothetical protein -
  LLE33_RS07920 (LLE33_07920) - 1517816..1518502 (-) 687 WP_010357532.1 phage replication initiation protein, NGO0469 family -
  LLE33_RS07925 (LLE33_07925) - 1518571..1518732 (-) 162 WP_003691530.1 hypothetical protein -
  LLE33_RS07930 (LLE33_07930) - 1518729..1519004 (-) 276 WP_033911205.1 NGO1622 family putative holin -
  LLE33_RS07935 (LLE33_07935) - 1519157..1519489 (-) 333 WP_003695500.1 hypothetical protein -
  LLE33_RS07940 (LLE33_07940) - 1519630..1519825 (-) 196 Protein_1545 hypothetical protein -
  LLE33_RS07945 (LLE33_07945) - 1520035..1520796 (+) 762 WP_012503753.1 hypothetical protein -
  LLE33_RS07950 (LLE33_07950) - 1520885..1521229 (-) 345 WP_229931773.1 hypothetical protein -
  LLE33_RS07955 (LLE33_07955) - 1521310..1521894 (-) 585 WP_003693477.1 Panacea domain-containing protein -
  LLE33_RS07960 (LLE33_07960) - 1522076..1522477 (-) 402 WP_003691454.1 type II toxin-antitoxin system HicB family antitoxin -
  LLE33_RS07965 (LLE33_07965) - 1522579..1522761 (-) 183 WP_003689143.1 type II toxin-antitoxin system HicA family toxin -
  LLE33_RS07970 (LLE33_07970) - 1522931..1523749 (-) 819 WP_003693474.1 DUF3037 domain-containing protein -
  LLE33_RS07975 (LLE33_07975) - 1524024..1524779 (-) 756 WP_003693472.1 LexA family transcriptional regulator -
  LLE33_RS07980 (LLE33_07980) - 1524916..1525101 (+) 186 WP_002238713.1 Cro/CI family transcriptional regulator -
  LLE33_RS07985 (LLE33_07985) - 1525190..1525345 (+) 156 WP_003698902.1 hypothetical protein -
  LLE33_RS07990 (LLE33_07990) - 1525322..1525510 (-) 189 WP_003691445.1 hypothetical protein -
  LLE33_RS07995 (LLE33_07995) - 1525683..1525910 (+) 228 WP_003691442.1 helix-turn-helix domain-containing protein -
  LLE33_RS11970 - 1525907..1526951 (+) 1045 Protein_1557 helix-turn-helix domain-containing protein -
  LLE33_RS08010 (LLE33_08010) - 1526966..1527745 (+) 780 WP_025455898.1 ATP-binding protein -
  LLE33_RS08015 (LLE33_08015) - 1527738..1527968 (+) 231 WP_012503908.1 hypothetical protein -
  LLE33_RS08020 (LLE33_08020) - 1528059..1528553 (+) 495 WP_003693463.1 DUF3310 domain-containing protein -
  LLE33_RS08025 (LLE33_08025) - 1528748..1528897 (+) 150 WP_033911194.1 phage associated protein -
  LLE33_RS08030 (LLE33_08030) - 1528925..1529206 (+) 282 WP_003689109.1 hypothetical protein -
  LLE33_RS08035 (LLE33_08035) - 1529197..1529577 (+) 381 WP_033911195.1 RusA family crossover junction endodeoxyribonuclease -
  LLE33_RS08040 (LLE33_08040) - 1529594..1529722 (-) 129 WP_017147221.1 hypothetical protein -
  LLE33_RS08045 (LLE33_08045) - 1529906..1530868 (-) 963 WP_050160654.1 IS110 family transposase -
  LLE33_RS08050 (LLE33_08050) - 1531380..1531739 (-) 360 WP_003689732.1 hypothetical protein -
  LLE33_RS08055 (LLE33_08055) - 1531860..1532945 (-) 1086 WP_003700139.1 zonular occludens toxin domain-containing protein -
  LLE33_RS08060 (LLE33_08060) - 1532955..1533245 (-) 291 WP_003700141.1 DUF2523 domain-containing protein -
  LLE33_RS08065 (LLE33_08065) - 1533246..1534811 (-) 1566 WP_167550560.1 IgG-binding virulence factor TspB family protein -
  LLE33_RS08070 (LLE33_08070) - 1534753..1535070 (-) 318 WP_003689167.1 DUF1132 family protein -
  LLE33_RS08075 (LLE33_08075) - 1535198..1535476 (-) 279 WP_003689168.1 hypothetical protein -
  LLE33_RS08080 (LLE33_08080) - 1535483..1535701 (-) 219 WP_003691584.1 major capsid protein -
  LLE33_RS08085 (LLE33_08085) - 1535775..1535972 (-) 198 WP_003689600.1 hypothetical protein -
  LLE33_RS08090 (LLE33_08090) - 1535977..1536267 (-) 291 WP_002216601.1 hypothetical protein -
  LLE33_RS08095 (LLE33_08095) - 1536312..1537659 (-) 1348 Protein_1575 replication initiation factor domain-containing protein -
  LLE33_RS08100 (LLE33_08100) - 1537798..1538220 (-) 423 WP_003691751.1 very short patch repair endonuclease -
  LLE33_RS08105 (LLE33_08105) - 1538226..1538822 (-) 597 WP_012503916.1 TIGR02391 family protein -
  LLE33_RS08110 (LLE33_08110) - 1539012..1539869 (-) 858 WP_012503917.1 ATP-binding protein -
  LLE33_RS08115 (LLE33_08115) - 1539883..1540212 (-) 330 WP_002234365.1 DNA cytosine methyltransferase -
  LLE33_RS08120 (LLE33_08120) - 1540251..1540859 (-) 609 WP_080229275.1 DNA cytosine methyltransferase -
  LLE33_RS08125 (LLE33_08125) - 1541228..1541374 (+) 147 WP_003691757.1 hypothetical protein -
  LLE33_RS08130 (LLE33_08130) comP 1541751..1542200 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene

Sequence


Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=734693 LLE33_RS08130 WP_002214937.1 1541751..1542200(-) (comP) [Neisseria gonorrhoeae strain 10610]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=734693 LLE33_RS08130 WP_002214937.1 1541751..1542200(-) (comP) [Neisseria gonorrhoeae strain 10610]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1

  comP Neisseria meningitidis 8013

99.329

100

0.993

  comP Neisseria subflava NJ9703

49.66

98.658

0.49