Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   LLE30_RS11030 Genome accession   NZ_CP106765
Coordinates   2097762..2099015 (+) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain 10500     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2092762..2104015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLE30_RS11010 (LLE30_11010) - 2093513..2094514 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  LLE30_RS11015 (LLE30_11015) - 2094608..2095456 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  LLE30_RS11020 (LLE30_11020) - 2095482..2095964 (+) 483 WP_003694396.1 CinA family protein -
  LLE30_RS11025 (LLE30_11025) msrAB 2096048..2097616 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  LLE30_RS11030 (LLE30_11030) pilA 2097762..2099015 (+) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  LLE30_RS11035 (LLE30_11035) - 2099286..2100065 (-) 780 WP_263060538.1 opacity family porin -
  LLE30_RS11995 pilE 2100478..2100687 (-) 210 WP_396954008.1 pilin Machinery gene
  LLE30_RS12000 pilE 2100684..2100980 (-) 297 WP_396954009.1 pilin Machinery gene
  LLE30_RS11045 (LLE30_11045) - 2101345..2101494 (-) 150 WP_263060532.1 hypothetical protein -
  LLE30_RS11055 (LLE30_11055) - 2101797..2102137 (-) 341 Protein_2133 pilin -
  LLE30_RS11060 (LLE30_11060) - 2102177..2102572 (-) 396 Protein_2134 pilin -
  LLE30_RS11065 (LLE30_11065) pilE 2103131..2103535 (-) 405 WP_229433471.1 pilin Machinery gene

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=734656 LLE30_RS11030 WP_003687004.1 2097762..2099015(+) (pilA) [Neisseria gonorrhoeae strain 10500]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=734656 LLE30_RS11030 WP_003687004.1 2097762..2099015(+) (pilA) [Neisseria gonorrhoeae strain 10500]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGTTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCGGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGTCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998