Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SAP2_RS04780 Genome accession   NZ_AP019698
Coordinates   1006636..1007265 (+) Length   209 a.a.
NCBI ID   WP_002509181.1    Uniprot ID   A0A7V7SP96
Organism   Staphylococcus arlettae strain P2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1001636..1012265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAP2_RS04755 (SAP2_09650) - 1002495..1003481 (-) 987 WP_142019532.1 FUSC family protein -
  SAP2_RS04760 (SAP2_09660) map 1003647..1004399 (+) 753 WP_021459027.1 type I methionyl aminopeptidase -
  SAP2_RS04765 (SAP2_09670) - 1004502..1004888 (+) 387 WP_002509178.1 hypothetical protein -
  SAP2_RS04770 (SAP2_09680) liaF 1004905..1005606 (+) 702 WP_002509179.1 cell wall-active antibiotics response protein LiaF -
  SAP2_RS04775 (SAP2_09690) vraS 1005603..1006646 (+) 1044 WP_002509180.1 sensor histidine kinase Regulator
  SAP2_RS04780 (SAP2_09700) vraR 1006636..1007265 (+) 630 WP_002509181.1 response regulator transcription factor Regulator
  SAP2_RS04785 (SAP2_09710) - 1007326..1008405 (-) 1080 WP_142019533.1 YihY/virulence factor BrkB family protein -
  SAP2_RS04790 (SAP2_09720) - 1008685..1008969 (-) 285 WP_002509183.1 hypothetical protein -
  SAP2_RS04795 (SAP2_09730) - 1008976..1009440 (-) 465 WP_142019534.1 low molecular weight protein-tyrosine-phosphatase -
  SAP2_RS04800 (SAP2_09740) - 1009576..1009779 (+) 204 WP_142019535.1 DUF1128 family protein -
  SAP2_RS04805 (SAP2_09750) - 1009791..1011029 (+) 1239 WP_112369296.1 aminopeptidase -
  SAP2_RS04810 (SAP2_09760) - 1011069..1011590 (+) 522 WP_142019536.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23587.12 Da        Isoelectric Point: 4.7606

>NTDB_id=73306 SAP2_RS04780 WP_002509181.1 1006636..1007265(+) (vraR) [Staphylococcus arlettae strain P2]
MPIKVLFVDDHEMVRIGISSYLSTQQDIEVVGEGKSGNEAIELAHKLQPDLILMDLVMDDMDGVDATAQVKKDLPQIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAVRKTYHGEAVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=73306 SAP2_RS04780 WP_002509181.1 1006636..1007265(+) (vraR) [Staphylococcus arlettae strain P2]
ATGCCAATTAAAGTATTATTTGTAGATGACCATGAAATGGTTCGTATTGGAATTTCTAGTTATTTATCAACACAACAAGA
TATAGAAGTAGTAGGCGAAGGTAAGTCAGGTAATGAAGCAATTGAATTAGCACATAAGTTACAACCCGATTTAATATTAA
TGGATTTAGTTATGGATGATATGGATGGGGTAGATGCAACTGCGCAAGTAAAAAAAGACTTACCGCAAATTAAAGTAGTT
ATGTTAACAAGTTATATAGAAGATAATGAAGTATATCGTGCGTTAGATTCAGGTGTAGATAGCTATATTTTAAAAACTAC
AAGTGCAAGTGATATTGCCGAAGCGGTGCGTAAGACATATCATGGTGAGGCTGTGTTTGAAGCAGAAGTATTAGTGAAAA
TGCGTAATCGTATGAAACAACGTGCTGAGCTTTATGAGATGTTGACAGAGCGAGAGATGGAAATATTATTGTTAATTGCT
AAAGGTTATTCTAACCAAGAAATTGCTAGCGCATCACACATTACTATTAAAACAGTTAAAACACACGTAAGTAATATATT
AAGTAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7V7SP96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment