Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P5709_RS18715 Genome accession   NZ_CP120557
Coordinates   3826795..3827385 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B771     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3821795..3832385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5709_RS18680 (P5709_18680) yidF 3821911..3822408 (+) 498 WP_000148063.1 radical SAM protein -
  P5709_RS18685 (P5709_18685) emrD 3822416..3823600 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  P5709_RS18690 (P5709_18690) ysdE 3823682..3823756 (+) 75 WP_211180519.1 protein YsdE -
  P5709_RS18695 (P5709_18695) tisB 3823880..3823969 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  P5709_RS18700 (P5709_18700) ivbL 3824534..3824632 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  P5709_RS18705 (P5709_18705) ilvB 3824738..3826426 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  P5709_RS18710 (P5709_18710) ilvN 3826430..3826720 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  P5709_RS18715 (P5709_18715) letA 3826795..3827385 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  P5709_RS18720 (P5709_18720) uhpB 3827385..3828887 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  P5709_RS18725 (P5709_18725) uhpC 3828897..3830216 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  P5709_RS18730 (P5709_18730) uhpT 3830354..3831745 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=732352 P5709_RS18715 WP_000633668.1 3826795..3827385(+) (letA) [Escherichia coli strain B771]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=732352 P5709_RS18715 WP_000633668.1 3826795..3827385(+) (letA) [Escherichia coli strain B771]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378