Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FLY91_RS06780 Genome accession   NZ_AP024560
Coordinates   1444996..1445628 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain NIPH17_0020     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1439996..1450628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FLY91_RS06755 yhfG 1440128..1440295 (+) 168 WP_000736860.1 YhfG family protein -
  FLY91_RS06760 fic 1440285..1440887 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  FLY91_RS06765 pabA 1440919..1441482 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  FLY91_RS06770 argD 1441568..1442788 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FLY91_RS06775 yhfK 1442855..1444945 (-) 2091 WP_001356225.1 YccS/YhfK family putative transporter -
  FLY91_RS06780 crp 1444996..1445628 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FLY91_RS06785 yhfA 1445930..1446334 (+) 405 WP_001148908.1 OsmC family protein -
  FLY91_RS06790 prkB 1446389..1447258 (-) 870 WP_001274680.1 phosphoribulokinase -
  FLY91_RS06795 yheU 1447312..1447530 (-) 219 WP_000907085.1 YheU family protein -
  FLY91_RS06800 yheT 1447524..1448546 (-) 1023 WP_000057380.1 hydrolase -
  FLY91_RS06805 yheS 1448546..1450459 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=73234 FLY91_RS06780 WP_000242755.1 1444996..1445628(-) (crp) [Escherichia coli strain NIPH17_0020]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=73234 FLY91_RS06780 WP_000242755.1 1444996..1445628(-) (crp) [Escherichia coli strain NIPH17_0020]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment