Detailed information NTG0073027

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: LDO00_RS21320
• Genome accession: NZ_AP024521
• Coordinates: 4391054..4392079 (-)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain E189
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4386054..4397079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LDO00_RS21290 (NIAHE189_40910)	zapB	4386138..4386383 (+)	246	WP_001296623.1	septal ring assembly protein ZapB	-
LDO00_RS21295 (NIAHE189_40920)	rraA	4386468..4386953 (-)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
LDO00_RS21300 (NIAHE189_40930)	menA	4387046..4387972 (-)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
LDO00_RS21305 (NIAHE189_40940)	hslU	4388039..4389370 (-)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
LDO00_RS21310 (NIAHE189_40950)	hslV	4389380..4389910 (-)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
LDO00_RS21315 (NIAHE189_40960)	ftsN	4390003..4390962 (-)	960	WP_000068834.1	cell division protein FtsN	-
LDO00_RS21320 (NIAHE189_40970)	cytR	4391054..4392079 (-)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
LDO00_RS21325 (NIAHE189_40980)	priA	4392235..4394433 (-)	2199	WP_001298972.1	primosomal protein N'	Machinery gene
LDO00_RS21330 (NIAHE189_40990)	rpmE	4394636..4394848 (+)	213	WP_000710769.1	50S ribosomal protein L31	-
LDO00_RS21335 (NIAHE189_41000)	-	4394903..4395526 (-)	624	WP_001402674.1	TIGR02117 family protein	-
LDO00_RS21340 (NIAHE189_41010)	yiiX	4395533..4396141 (-)	609	WP_001402675.1	YiiX family permuted papain-like enzyme	-
LDO00_RS21345 (NIAHE189_41020)	metJ	4396201..4396518 (-)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=73027 LDO00_RS21320 WP_000644904.1 4391054..4392079(-) (cytR) [Escherichia coli strain E189]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=73027 LDO00_RS21320 WP_000644904.1 4391054..4392079(-) (cytR) [Escherichia coli strain E189]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTCGCACCGGAACTGGAG
CTACCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATCTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628