Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P1J22_RS10170 Genome accession   NZ_CP119734
Coordinates   1981878..1982534 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E92     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1976878..1987534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1J22_RS10135 (P1J22_10135) - 1977507..1978067 (+) 561 Protein_2000 aromatic amino acid transport family protein -
  P1J22_RS10140 (P1J22_10140) yecA 1978129..1978794 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  P1J22_RS10160 (P1J22_10160) pgsA 1979444..1979992 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P1J22_RS10165 (P1J22_10165) uvrC 1980049..1981881 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  P1J22_RS10170 (P1J22_10170) letA 1981878..1982534 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P1J22_RS29205 - 1982676..1982747 (+) 72 Protein_2005 transcriptional regulator -
  P1J22_RS10175 (P1J22_10175) yecU 1982830..1983006 (+) 177 WP_000590347.1 protein YecU -
  P1J22_RS10180 (P1J22_10180) yecF 1982993..1983217 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  P1J22_RS10185 (P1J22_10185) sdiA 1983285..1984007 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  P1J22_RS10190 (P1J22_10190) tcyN 1984237..1984989 (-) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P1J22_RS10195 (P1J22_10195) tcyL 1984986..1985654 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  P1J22_RS10200 (P1J22_10200) dcyD 1985669..1986655 (-) 987 WP_001128218.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=727933 P1J22_RS10170 WP_000611335.1 1981878..1982534(-) (letA) [Escherichia coli strain E92]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=727933 P1J22_RS10170 WP_000611335.1 1981878..1982534(-) (letA) [Escherichia coli strain E92]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486