Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P3M65_RS14935 Genome accession   NZ_CP119719
Coordinates   3045324..3045914 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain IZSBS22     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3040324..3050914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3M65_RS14920 uhpT 3040846..3042237 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  P3M65_RS14925 uhpC 3042493..3043812 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  P3M65_RS14930 uhpB 3043822..3045324 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  P3M65_RS14935 letA 3045324..3045914 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  P3M65_RS14940 ilvN 3045989..3046279 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  P3M65_RS14945 ilvB 3046283..3047971 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  P3M65_RS14950 ivbL 3048077..3048175 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  P3M65_RS14955 tisB 3048739..3048828 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  P3M65_RS14960 ysdE 3049091..3049165 (-) 75 WP_211180519.1 protein YsdE -
  P3M65_RS14965 emrD 3049247..3050431 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=727709 P3M65_RS14935 WP_000633668.1 3045324..3045914(-) (letA) [Escherichia coli strain IZSBS22]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=727709 P3M65_RS14935 WP_000633668.1 3045324..3045914(-) (letA) [Escherichia coli strain IZSBS22]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378