Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NZD48_RS04565 Genome accession   NZ_CP103964
Coordinates   966183..966812 (+) Length   209 a.a.
NCBI ID   WP_039644795.1    Uniprot ID   A0A0A8HRY9
Organism   Staphylococcus hyicus strain MM2101     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 961183..971812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NZD48_RS04540 (NZD48_04540) - 961877..962902 (-) 1026 WP_039644788.1 aromatic acid exporter family protein -
  NZD48_RS04545 (NZD48_04545) map 963196..963954 (+) 759 WP_259490265.1 type I methionyl aminopeptidase -
  NZD48_RS04550 (NZD48_04550) - 964053..964439 (+) 387 WP_052257806.1 hypothetical protein -
  NZD48_RS04555 (NZD48_04555) liaF 964452..965153 (+) 702 WP_259490268.1 cell wall-active antibiotics response protein LiaF -
  NZD48_RS04560 (NZD48_04560) vraS 965150..966193 (+) 1044 WP_252538285.1 sensor histidine kinase Regulator
  NZD48_RS04565 (NZD48_04565) vraR 966183..966812 (+) 630 WP_039644795.1 response regulator transcription factor Regulator
  NZD48_RS04570 (NZD48_04570) - 966876..967445 (-) 570 WP_252538287.1 carbonic anhydrase -
  NZD48_RS04575 (NZD48_04575) - 967480..968751 (-) 1272 WP_259490271.1 YihY/virulence factor BrkB family protein -
  NZD48_RS04580 (NZD48_04580) - 968871..969146 (-) 276 WP_039644801.1 hypothetical protein -
  NZD48_RS04585 (NZD48_04585) - 969153..969611 (-) 459 WP_039644802.1 low molecular weight protein-tyrosine-phosphatase -
  NZD48_RS04590 (NZD48_04590) - 969744..969953 (+) 210 WP_039644804.1 DUF1128 family protein -
  NZD48_RS04595 (NZD48_04595) - 969970..971205 (+) 1236 WP_259490274.1 aminopeptidase -
  NZD48_RS04600 (NZD48_04600) - 971219..971737 (+) 519 WP_252538296.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23540.17 Da        Isoelectric Point: 5.1671

>NTDB_id=726642 NZD48_RS04565 WP_039644795.1 966183..966812(+) (vraR) [Staphylococcus hyicus strain MM2101]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAITKAHELQPDLILMDLVMTDMDGVEATTQIKKDLPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIAEAIRKTHKGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=726642 NZD48_RS04565 WP_039644795.1 966183..966812(+) (vraR) [Staphylococcus hyicus strain MM2101]
ATGACAATTAAAGTATTATTTGTGGATGATCATGAAATGGTAAGAATTGGAATATCAAGTTATCTTTCAACTCAACCAGA
TATTGAAGTAGTTGGTGAAGGAGCATCTGGTAAAGAAGCGATTACGAAGGCGCATGAACTTCAACCGGATTTGATTTTAA
TGGACTTAGTGATGACAGATATGGATGGTGTAGAAGCGACGACTCAAATTAAAAAAGATTTACCACGTATTAAAGTCGTG
ATGCTTACAAGCTATATTGAAGATAAAGAAGTTTACCGTGCGTTAGATGCAGGGGTGGACAGTTATATATTAAAAACAAC
AAGTGCAAGTGATATAGCCGAAGCAATTCGTAAAACACATAAAGGTGAATCTGTTTTTGAAGCTGAAGTGCTAGTGAAAA
TGCGAAACCGTATGAGACAAAGAGCAGAACTTTATGAATTATTAACGGAACGTGAAATGGAAATATTGTTACTGATTTCC
AAAGGGTACTCAAATCAGGAAATTGCGAGCGCCTCTCATATAACGATAAAGACGGTAAAAACGCATGTTAGTAACATTTT
AAGTAAGCTTGAAGTACAAGACCGTACACAAGCAGTTATTTATGCCTTTCAACATGGCTTAATTGAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A8HRY9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383