Detailed information NTG0726641

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NZD48_RS04560
• Genome accession: NZ_CP103964
• Coordinates: 965150..966193 (+)
• Length: 347 a.a.
• NCBI ID: WP_252538285.1
• Uniprot ID: -
• Organism: Staphylococcus hyicus strain MM2101
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 960150..971193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NZD48_RS04535 (NZD48_04535)	-	961034..961765 (+)	732	WP_259490263.1	type 1 glutamine amidotransferase	-
NZD48_RS04540 (NZD48_04540)	-	961877..962902 (-)	1026	WP_039644788.1	aromatic acid exporter family protein	-
NZD48_RS04545 (NZD48_04545)	map	963196..963954 (+)	759	WP_259490265.1	type I methionyl aminopeptidase	-
NZD48_RS04550 (NZD48_04550)	-	964053..964439 (+)	387	WP_052257806.1	hypothetical protein	-
NZD48_RS04555 (NZD48_04555)	liaF	964452..965153 (+)	702	WP_259490268.1	cell wall-active antibiotics response protein LiaF	-
NZD48_RS04560 (NZD48_04560)	vraS	965150..966193 (+)	1044	WP_252538285.1	sensor histidine kinase	Regulator
NZD48_RS04565 (NZD48_04565)	vraR	966183..966812 (+)	630	WP_039644795.1	response regulator transcription factor	Regulator
NZD48_RS04570 (NZD48_04570)	-	966876..967445 (-)	570	WP_252538287.1	carbonic anhydrase	-
NZD48_RS04575 (NZD48_04575)	-	967480..968751 (-)	1272	WP_259490271.1	YihY/virulence factor BrkB family protein	-
NZD48_RS04580 (NZD48_04580)	-	968871..969146 (-)	276	WP_039644801.1	hypothetical protein	-
NZD48_RS04585 (NZD48_04585)	-	969153..969611 (-)	459	WP_039644802.1	low molecular weight protein-tyrosine-phosphatase	-
NZD48_RS04590 (NZD48_04590)	-	969744..969953 (+)	210	WP_039644804.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39862.79 Da
• Isoelectric Point: 4.7854

>NTDB_id=726641 NZD48_RS04560 WP_252538285.1 965150..966193(+) (vraS) [Staphylococcus hyicus strain MM2101]
MNQYVRSIGSMLILVYSLFTAFFFIDNVFTNIIFFQGMFYTQIFGIPVFLFLNLITIFLCIIVGSVLAYKNNQQSDWLKA
QIERAIEGETVGVNDQQIEIYQETLELYEALVPLNQELHRMRIKTQNLTNESYNINDSKVQKIIEDERHRLARELHDSVS
QQLFAASMMLSAIKETPLDPPLNQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIQTLVTDLQRKVPLNVVQDI
GEFDVPKGMEDHLFRITQEAISNTLRHSKGTEVTVELLQREDYILLRIQDDGIGFNVDEKMEQSYGLKNMRERAMEIGAT
FHIVSLPDSGTRIEVKAPLDKEGHNDN

Nucleotide

• Length: 1044 bp

>NTDB_id=726641 NZD48_RS04560 WP_252538285.1 965150..966193(+) (vraS) [Staphylococcus hyicus strain MM2101]
ATGAATCAATATGTACGATCGATAGGTTCAATGCTAATACTTGTGTATAGTTTATTTACAGCTTTCTTTTTTATCGACAA
TGTTTTCACAAATATCATTTTTTTCCAAGGTATGTTTTATACGCAAATATTTGGGATTCCAGTATTTTTGTTTTTAAACC
TTATTACTATATTTTTATGTATTATCGTAGGAAGTGTGCTTGCATATAAAAACAATCAACAAAGCGATTGGTTGAAGGCG
CAAATTGAGCGTGCCATTGAAGGTGAAACGGTAGGTGTCAATGATCAACAAATCGAAATTTATCAAGAAACGTTAGAACT
TTATGAAGCATTAGTGCCACTTAATCAAGAATTACATCGTATGCGCATTAAAACACAAAATTTAACGAATGAGTCTTATA
ATATAAATGACTCAAAAGTACAAAAAATAATTGAGGATGAACGACATCGCCTCGCTAGAGAATTACATGATAGCGTGTCA
CAACAATTATTTGCGGCAAGTATGATGCTTTCAGCAATTAAAGAAACACCTTTAGATCCACCTTTGAACCAGCAAATACC
GACACTTGAAAAAATGGTCCAGGATTCACAACTTGAAATGCGCGCACTCTTGTTACATTTACGACCTATAGGATTGAAGG
ACAAGTCATTAGGAGAAGGCATTCAAACTTTAGTTACTGATCTTCAGCGTAAGGTACCTTTAAATGTCGTGCAGGATATT
GGTGAGTTTGATGTTCCAAAAGGTATGGAAGATCATTTGTTTAGAATTACCCAAGAAGCCATTTCTAATACATTACGTCA
TTCTAAAGGGACTGAAGTGACCGTAGAATTATTACAACGTGAAGATTACATACTGTTACGTATTCAAGATGATGGTATCG
GCTTTAATGTTGATGAAAAAATGGAACAAAGCTATGGCTTAAAAAATATGCGTGAGCGCGCAATGGAAATAGGCGCAACA
TTTCATATCGTATCTTTACCTGACTCAGGAACGAGAATTGAAGTGAAAGCACCATTAGACAAGGAGGGGCACAATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (250-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	81.556	100	0.816