Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PWR57_RS24070 Genome accession   NZ_CP119441
Coordinates   4791244..4791834 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O121 strain 201805972     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4786244..4796834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWR57_RS24055 (PWR57_24025) uhpT 4786884..4788275 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PWR57_RS24060 (PWR57_24030) uhpC 4788413..4789732 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PWR57_RS24065 (PWR57_24035) uhpB 4789742..4791244 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PWR57_RS24070 (PWR57_24040) letA 4791244..4791834 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PWR57_RS24075 (PWR57_24045) ilvN 4791909..4792199 (-) 291 WP_001181705.1 acetolactate synthase small subunit -
  PWR57_RS24080 (PWR57_24050) ilvB 4792203..4793891 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PWR57_RS24085 (PWR57_24055) ivbL 4793997..4794095 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PWR57_RS24090 (PWR57_24060) tisB 4794660..4794749 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PWR57_RS24095 (PWR57_24065) ysdE 4794873..4794947 (-) 75 WP_211180519.1 protein YsdE -
  PWR57_RS24100 (PWR57_24070) emrD 4795029..4796213 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PWR57_RS24105 (PWR57_24075) yidF 4796221..4796718 (-) 498 WP_000148062.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=726503 PWR57_RS24070 WP_000633668.1 4791244..4791834(-) (letA) [Escherichia coli O121 strain 201805972]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=726503 PWR57_RS24070 WP_000633668.1 4791244..4791834(-) (letA) [Escherichia coli O121 strain 201805972]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378