Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   PX811_RS09290 Genome accession   NZ_CP119404
Coordinates   1926212..1928044 (+) Length   610 a.a.
NCBI ID   WP_275772366.1    Uniprot ID   -
Organism   Escherichia coli strain MRE162 substr. UK     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1921212..1933044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PX811_RS09255 (PX811_001851) dcyD 1921438..1922424 (+) 987 WP_275772361.1 D-cysteine desulfhydrase -
  PX811_RS09260 (PX811_001852) tcyL 1922439..1923107 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PX811_RS09265 (PX811_001853) tcyN 1923104..1923856 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PX811_RS09270 (PX811_001854) sdiA 1924086..1924808 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PX811_RS09275 (PX811_001855) yecF 1924876..1925100 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PX811_RS09280 (PX811_001856) yecU 1925087..1925263 (-) 177 WP_000590347.1 protein YecU -
  PX811_RS23265 - 1925346..1925417 (-) 72 Protein_1813 transcriptional regulator -
  PX811_RS09285 (PX811_001857) letA 1925559..1926215 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PX811_RS09290 (PX811_001858) uvrC 1926212..1928044 (+) 1833 WP_275772366.1 excinuclease ABC subunit UvrC Machinery gene
  PX811_RS09295 (PX811_001859) pgsA 1928101..1928649 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PX811_RS09315 (PX811_001863) yecA 1929298..1929963 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  PX811_RS09320 (PX811_001864) tyrP 1930025..1931236 (-) 1212 WP_000797560.1 tyrosine transporter TyrP -
  PX811_RS09325 (PX811_001865) yecH 1931427..1931666 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  PX811_RS09330 (PX811_001866) ftnA 1931704..1932201 (-) 498 WP_000917208.1 non-heme ferritin -
  PX811_RS09335 (PX811_001867) yecR 1932372..1932695 (-) 324 WP_001237869.1 YecR-like lipofamily protein -
  PX811_RS09340 (PX811_001868) azuC 1932958..1933044 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68220.07 Da        Isoelectric Point: 9.3685

>NTDB_id=726289 PX811_RS09290 WP_275772366.1 1926212..1928044(+) (uvrC) [Escherichia coli strain MRE162 substr. UK]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHVKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRTCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=726289 PX811_RS09290 WP_275772366.1 1926212..1928044(+) (uvrC) [Escherichia coli strain MRE162 substr. UK]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGTCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTACGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTTACAGCACTTGCCAGTGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374