Detailed information NTG0072627

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: J3989_RS02895
• Genome accession: NZ_AP024489
• Coordinates: 583049..583633 (-)
• Length: 194 a.a.
• NCBI ID: WP_002218660.1
• Uniprot ID: A9M3B7
• Organism: Neisseria meningitidis strain NIID777
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 578049..588633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J3989_RS02860 (NMNIID777_05270)	-	578326..578625 (+)	300	WP_002215645.1	DUF2818 family protein	-
J3989_RS02865 (NMNIID777_05290)	-	578734..579630 (-)	897	WP_127210114.1	polyprenyl synthetase family protein	-
J3989_RS02870 (NMNIID777_05300)	-	579614..579877 (-)	264	WP_306461078.1	exodeoxyribonuclease VII small subunit	-
J3989_RS10770	-	579986..580075 (-)	90	Protein_558	exodeoxyribonuclease VII	-
J3989_RS02880 (NMNIID777_05310)	rsgA	580102..581025 (-)	924	WP_002226945.1	ribosome small subunit-dependent GTPase A	-
J3989_RS02885 (NMNIID777_05320)	-	581030..582886 (-)	1857	WP_207177323.1	ABC transporter ATP-binding protein	-
J3989_RS02890	-	582912..583049 (-)	138	WP_002215654.1	hypothetical protein	-
J3989_RS02895 (NMNIID777_05330)	ruvA	583049..583633 (-)	585	WP_002218660.1	Holliday junction branch migration protein RuvA	Machinery gene
J3989_RS02900 (NMNIID777_05340)	-	583715..584041 (-)	327	WP_002218661.1	PepSY domain-containing protein	-
J3989_RS02905 (NMNIID777_05350)	-	584095..584814 (-)	720	WP_002226003.1	septal ring lytic transglycosylase RlpA family protein	-
J3989_RS02910	-	584811..584933 (-)	123	WP_009346050.1	hypothetical protein	-
J3989_RS02915 (NMNIID777_05360)	trmL	584944..585408 (-)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
J3989_RS02920 (NMNIID777_05370)	-	585473..586198 (-)	726	WP_002255650.1	ComF family protein	-
J3989_RS02925 (NMNIID777_05380)	bioH	586197..586946 (+)	750	WP_002224839.1	pimeloyl-ACP methyl ester esterase BioH	-
J3989_RS02930 (NMNIID777_05390)	-	586943..587731 (+)	789	WP_207177219.1	methyltransferase	-
J3989_RS02935 (NMNIID777_05400)	-	587919..588188 (+)	270	WP_002221591.1	hypothetical protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20659.85 Da
• Isoelectric Point: 5.1063

>NTDB_id=72627 J3989_RS02895 WP_002218660.1 583049..583633(-) (ruvA) [Neisseria meningitidis strain NIID777]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLA
LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=72627 J3989_RS02895 WP_002218660.1 583049..583633(-) (ruvA) [Neisseria meningitidis strain NIID777]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAAACATTCCGCCAACTGATCAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCAGGCGGTTGCAGAAGAAGACGT
GAAACGCCTGTCTTCCGCGCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAGCGAACGCGAAGCAAAAGCGGCGGTCAAAGGCGTTCCGGAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• RuvA, C-terminal domain (RuvA_C) (150-192)

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

3D structure

• AlphaFold DB: A9M3B7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.922	100	0.381