Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PYZ88_RS13465 Genome accession   NZ_CP119120
Coordinates   2742128..2742784 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain GENOMIC22-004     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2737128..2747784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYZ88_RS13435 (PYZ88_13430) yecA 2738379..2739044 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  PYZ88_RS13455 (PYZ88_13450) pgsA 2739694..2740242 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PYZ88_RS13460 (PYZ88_13455) uvrC 2740299..2742131 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PYZ88_RS13465 (PYZ88_13460) letA 2742128..2742784 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PYZ88_RS25630 - 2742926..2742997 (+) 72 Protein_2621 transcriptional regulator -
  PYZ88_RS13470 (PYZ88_13465) yecU 2743080..2743256 (+) 177 WP_000590347.1 protein YecU -
  PYZ88_RS13475 (PYZ88_13470) yecF 2743243..2743467 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PYZ88_RS13480 (PYZ88_13475) sdiA 2743534..2744256 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  PYZ88_RS13485 (PYZ88_13480) tcyN 2744486..2745238 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PYZ88_RS13490 (PYZ88_13485) tcyL 2745235..2745903 (-) 669 WP_032162420.1 cystine ABC transporter permease -
  PYZ88_RS13495 (PYZ88_13490) dcyD 2745918..2746904 (-) 987 WP_265206824.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=724989 PYZ88_RS13465 WP_000611335.1 2742128..2742784(-) (letA) [Escherichia coli strain GENOMIC22-004]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=724989 PYZ88_RS13465 WP_000611335.1 2742128..2742784(-) (letA) [Escherichia coli strain GENOMIC22-004]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486