Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PY721_RS15680 Genome accession   NZ_CP119008
Coordinates   3199126..3199716 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CE0011b     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3194126..3204716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY721_RS15665 (PY721_15665) uhpT 3194766..3196157 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PY721_RS15670 (PY721_15670) uhpC 3196295..3197614 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PY721_RS15675 (PY721_15675) uhpB 3197624..3199126 (-) 1503 WP_105906406.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PY721_RS15680 (PY721_15680) letA 3199126..3199716 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PY721_RS15685 (PY721_15685) ilvN 3199792..3200082 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PY721_RS15690 (PY721_15690) ilvB 3200086..3201774 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PY721_RS15695 (PY721_15695) ivbL 3201880..3201978 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PY721_RS15700 (PY721_15700) tisB 3202543..3202632 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  PY721_RS15705 (PY721_15705) ysdE 3202756..3202830 (-) 75 WP_211180519.1 protein YsdE -
  PY721_RS15710 (PY721_15710) emrD 3202912..3204096 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PY721_RS15715 (PY721_15715) yidF 3204104..3204601 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=724653 PY721_RS15680 WP_000633668.1 3199126..3199716(-) (letA) [Escherichia coli strain CE0011b]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=724653 PY721_RS15680 WP_000633668.1 3199126..3199716(-) (letA) [Escherichia coli strain CE0011b]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378