Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EKM74_RS13685 Genome accession   NZ_AP019306
Coordinates   2579391..2580377 (+) Length   328 a.a.
NCBI ID   WP_000959282.1    Uniprot ID   A0A7U7EXT8
Organism   Staphylococcus aureus strain TUM9463     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 2574391..2585377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS13660 opp4B 2574605..2575567 (+) 963 WP_000915997.1 oligopeptide ABC transporter permease -
  EKM74_RS13665 opp4C 2575579..2576460 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  EKM74_RS13670 trpS 2576502..2577491 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  EKM74_RS13675 spxA 2577785..2578180 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  EKM74_RS13680 mecA 2578551..2579270 (+) 720 WP_001217728.1 adaptor protein MecA -
  EKM74_RS13685 coiA 2579391..2580377 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  EKM74_RS13690 pepF 2580425..2582233 (+) 1809 WP_000082725.1 oligoendopeptidase F -
  EKM74_RS13695 yjbH 2582693..2583499 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  EKM74_RS13700 - 2583522..2583887 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  EKM74_RS13705 - 2583991..2584584 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  EKM74_RS13710 - 2584770..2585117 (+) 348 WP_001242103.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38878.55 Da        Isoelectric Point: 9.5714

>NTDB_id=72321 EKM74_RS13685 WP_000959282.1 2579391..2580377(+) (coiA) [Staphylococcus aureus strain TUM9463]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=72321 EKM74_RS13685 WP_000959282.1 2579391..2580377(+) (coiA) [Staphylococcus aureus strain TUM9463]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

100

100

1
  coiA Staphylococcus aureus MW2

97.561

100

0.976

Multiple sequence alignment