Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OU688_RS00195 Genome accession   NZ_CP118601
Coordinates   38790..39380 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain NB4833     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 33790..44380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OU688_RS00165 (OU688_00165) emrD 34272..35456 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  OU688_RS00170 (OU688_00170) ysdE 35538..35612 (+) 75 WP_211180519.1 protein YsdE -
  OU688_RS00175 (OU688_00175) tisB 35875..35964 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  OU688_RS00180 (OU688_00180) ivbL 36529..36627 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  OU688_RS00185 (OU688_00185) ilvB 36733..38421 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  OU688_RS00190 (OU688_00190) ilvN 38425..38715 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  OU688_RS00195 (OU688_00195) letA 38790..39380 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  OU688_RS00200 (OU688_00200) uhpB 39380..40882 (+) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  OU688_RS00205 (OU688_00205) uhpC 40892..42211 (+) 1320 WP_174785347.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  OU688_RS00210 (OU688_00210) uhpT 42349..43740 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=723069 OU688_RS00195 WP_000633668.1 38790..39380(+) (letA) [Escherichia coli strain NB4833]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=723069 OU688_RS00195 WP_000633668.1 38790..39380(+) (letA) [Escherichia coli strain NB4833]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378