Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PUW49_RS02255 Genome accession   NZ_CP118054
Coordinates   444875..445501 (+) Length   208 a.a.
NCBI ID   WP_274994886.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI37     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 439875..450501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS02235 (PUW49_02235) - 440311..441051 (+) 741 WP_022526377.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PUW49_RS02240 (PUW49_02240) stkP 441048..442922 (+) 1875 WP_024052108.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PUW49_RS02245 (PUW49_02245) liaF 443183..443881 (+) 699 WP_024052107.1 cell wall-active antibiotics response protein LiaF -
  PUW49_RS02250 (PUW49_02250) - 443878..444873 (+) 996 WP_024052106.1 sensor histidine kinase -
  PUW49_RS02255 (PUW49_02255) vraR 444875..445501 (+) 627 WP_274994886.1 response regulator transcription factor Regulator
  PUW49_RS02260 (PUW49_02260) - 445548..446948 (+) 1401 WP_070241554.1 Cof-type HAD-IIB family hydrolase -
  PUW49_RS02265 (PUW49_02265) - 446950..447321 (+) 372 WP_024052103.1 S1 RNA-binding domain-containing protein -
  PUW49_RS02270 (PUW49_02270) - 447455..447772 (-) 318 WP_024052102.1 DUF960 domain-containing protein -
  PUW49_RS02275 (PUW49_02275) - 447892..448425 (-) 534 WP_024052101.1 DUF402 domain-containing protein -
  PUW49_RS02280 (PUW49_02280) recX 448503..449288 (-) 786 WP_042754014.1 recombination regulator RecX -
  PUW49_RS02285 (PUW49_02285) - 449352..450128 (-) 777 WP_274994889.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 23504.08 Da        Isoelectric Point: 4.9072

>NTDB_id=720868 PUW49_RS02255 WP_274994886.1 444875..445501(+) (vraR) [Streptococcus anginosus strain VSI37]
MQILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVERALELRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPTR

Nucleotide


Download         Length: 627 bp        

>NTDB_id=720868 PUW49_RS02255 WP_274994886.1 444875..445501(+) (vraR) [Streptococcus anginosus strain VSI37]
ATGCAGATTTTATTAGTAGATGACCATGAAATGGTAAGACTTGGCTTAAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAGAGCTTTGGAGTTGCGTCCAGATGTGATTATGATGGACA
TTGTCATGCCTGAAATGAGTGGGATTGAAGCGACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGATGCGGGTGCTAAAGGATATATGCTCAAAACTTCTAGCGC
GGATGATATTTTACGAGCGGTCCGAAAAGTAGCCAAGGGTGAACTTGCTATTGAAACAGAAGTCAGCCAAAAAGTAGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTTCCCACAAGATGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

99.038

0.534
  degU Bacillus subtilis subsp. subtilis str. 168

38.767

100

0.423