Detailed information NTG0720831

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: PUW71_RS09660
• Genome accession: NZ_CP118053
• Coordinates: 1873169..1875730 (-)
• Length: 853 a.a.
• NCBI ID: WP_070242131.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain VSI40
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1868169..1880730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW71_RS09635 (PUW71_09635)	ruvA	1868241..1868831 (-)	591	WP_195916288.1	Holliday junction branch migration protein RuvA	Machinery gene
PUW71_RS09640 (PUW71_09640)	-	1868993..1869436 (+)	444	WP_024053224.1	helix-turn-helix transcriptional regulator	-
PUW71_RS09645 (PUW71_09645)	hexB	1869885..1871831 (-)	1947	WP_024053225.1	DNA mismatch repair endonuclease MutL	Machinery gene
PUW71_RS09650 (PUW71_09650)	-	1872085..1872525 (+)	441	WP_070242129.1	LytTR family DNA-binding domain-containing protein	-
PUW71_RS09655 (PUW71_09655)	-	1872522..1872980 (+)	459	WP_024053227.1	DUF3021 domain-containing protein	-
PUW71_RS09660 (PUW71_09660)	hexA	1873169..1875730 (-)	2562	WP_070242131.1	DNA mismatch repair protein MutS	Machinery gene
PUW71_RS09665 (PUW71_09665)	argR	1876099..1876539 (-)	441	WP_003027809.1	arginine repressor	-
PUW71_RS09670 (PUW71_09670)	argS	1876643..1878331 (+)	1689	WP_024053229.1	arginine--tRNA ligase	-
PUW71_RS09675 (PUW71_09675)	nrdI	1878386..1878841 (-)	456	WP_024053230.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
PUW71_RS09680 (PUW71_09680)	-	1878917..1879426 (-)	510	WP_024053231.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96106.88 Da
• Isoelectric Point: 5.0391

>NTDB_id=720831 PUW71_RS09660 WP_070242131.1 1873169..1875730(-) (hexA) [Streptococcus anginosus strain VSI40]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELSEMERQVLETQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLIENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKVIDSPVLEDLIAKLDEIPELASLIQSAISP
DAPNVITEGNIIKTGFDETLDKYRVVIRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTMATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIVVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMIEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQVNEKPSFGIFNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=720831 PUW71_RS09660 WP_070242131.1 1873169..1875730(-) (hexA) [Streptococcus anginosus strain VSI40]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGTTGTT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACCTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAATAGAGAATGCTCG
AACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGGATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACAGTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTGCCACAAATTAAGGGAATTTTAAAAGTAATTGATA
GCCCAGTTTTGGAAGATTTGATTGCAAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
ACGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACAAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTCTGAAAAATTCAGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGGGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTATGGCAACAGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTGTTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGATTGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCCACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCTAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGTAAATGAGAAGCCATCTTTTGGCATCTTTAATACATTA
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (255-546)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.671	100	0.767
mutS	Pseudomonas stutzeri strain ATCC 17587	36.227	100	0.367